One event, a medication error, in the degludec group was deemed to be serious. There were 3 confirmed adjudicated events in 3 participants in the icodec group (2 deaths and 1 ischemic stroke) and there were 2 events in 1 participant in the degludec group (1 acute myocardial infarction ...
medication-naïve or had discontinued metformin monotherapy [mean baseline HbA1c 59 ± 8 to 61 ± 8 mmol/mol (7.6 ± 0.7 to 7.8 ± 0.8%)] to once-weekly injections of placebo or dulaglutide (0.1, 0.5, 1.0 or 1.5 mg).Results A significant dose-dependent reduction in HbA1c (least ...
Once‐weekly Trulicity is a type 2 diabetes medication for adults that helps your body release its own insulin and can help improve your A1C and blood sugar numbers. For adults living with T2DM, Trulicity lowers the risk of CV events like heart attack, s
have type 2 diabetes and a history of diabetic retinopathy have or have had depression, suicidal thoughts, or mental health issues are pregnant or plan to become pregnant. Wegovy ® may harm your unborn baby. You should stop using Wegovy ® 2 months before you plan to become pregnant a...
“One of the biggest hurdles in drug development is translation between mice and humans. This is why we were excited that the benefits of NK2R agonism translated to diabetic and obese nonhuman primates, which represents a big step towards clinical translation,” says Ph.D. Student Frederike Sas...
a b s t r a c t Aim: To compare once- versus twice-daily insulindetemir addedonOADS therapy ininsulin- naive type 2 diabetes patients in terms of efficacy and safety. Methods: An open-label study performed at a single center, comprised a randomized, crossover 24 week with insulin-na...
Rescue medication, defined as intensification of background antidiabetic treatment or the initiation of new glucose-lowering medications, could be given to patients meeting specific criteria at the discretion of the investigator. The primary outcome was change in HbA1c from baseline at week 30, ...
This study aimed to assess the effect of omarigliptin on patients' psychological attitudes and responses compared with daily dipeptidyl peptidase-4 inhibitors (DPP4is) by measuring the burden of pharmacotherapy using the Diabetic Treatment Burden Questionnaire (DTBQ).#Patients with type 2 diabetes ...
Diabetic MedicineGrunberger G, Chang A, Garcia Soria G, Botros FT, Bsharat R, Milicevic Z. Monotherapy with the once-weekly GLP-1 analogue dulaglutide for 12 weeks in patients with type 2 diabetes: dose-dependent effects on glycaemic control in a randomized, double-blind, placebo-controlled...
For the diabetic group the definition was 130/85mm Hg. Tolerability and safety of antihypertensive drugs was assessed by physical examination and detection of adverse effects potentially related to antihypertensive medication. Results: At the end of the 8-week treatment period with quinapril, adequate ...