E. Omics-based hybrid prediction in maize. Theoretical and Applied Genetics 130:1927-1939 (2017).Westhues M, Schrag TA, Heuer C, Thaller G, Utz HF, Schipprack W, Thiemann A, Seifert F, Ehret A, Schlereth A, Stitt M, Nikoloski Z, Willmitzer L, Schon CC, Scholten S, Melchinger ...
AI-powered omics-based drug pair discovery for pyroptosis therapy targeting triple-negative breast cancer Boshu Ouyang, Caihua Shan, Shun Shen, Xinnan Dai, Qingwang Chen, Xiaomin Su, Yongbin Cao, Xifeng Qin, Ying He, Siyu Wang, Ruizhe Xu, Ruining Hu, Leming Shi, Tun Lu...
Studies on the genome and epigenome, transcriptome, proteome, together with other emerging omics such as metabolomics or lipidomics, contribute to the development of new CRC biomarkers. Case-control cohorts are typically used for biomarker discovery, using fresh frozen or paraffin tissue samples, ...
Salivaomics, urinomics, and milkomics appear as integrative omics that may develop a high potential for early and non-invasive diagnoses in BC. Thus, the analysis of the tumor circulome is considered a novel frontier in liquid biopsy. Omics-based investigations have applications in BC modeling,...
Due to low success rates and long cycles of traditional drug development, the clinical tendency is to apply omics techniques to reveal patient-level disease characteristics and individualized responses to treatment. However, the heterogeneous form of dat
On the other hand, an omics-based approach uses holistic, non-bias and integrative methods for a better understanding of the whole process [27]. The main advantage of using omics-based technologies is that researchers are now able to investigate multiple molecules (genes, proteins, and ...
Natural products are increasingly utilized in clinical settings, and lipidomics-based natural products therapy offers new insights for studying the treatment of CKD. 2. Lipids and lipidomics Lipids are essential constituents of biological membranes and are structurally and functionally diverse molecules [...
This study was conducted to develop biomarkers to identify 26 cultivars of Korean sweet potato (Ipomoea batatas L. Lam) using omics-based methods. Random amplification of polymorphic DNA (RAPD) markers revealed that 75 random 10-mer primers generated 50 polymorphic RAPD markers from the 28 Korean...
best predictors of PFCs distribution, and the Mediterranean Sea as an outlier in terms of PFCs composition. Our results demonstrate the potential of omics-based predictions of planktonic communities functional composition based on environmental data....
Omics-based re- sponses induced by bosentan in human hepatoma Hep- aRG cell cultures. Arch Toxicol. 2018;92:1939-52.Rodrigues RM, Kollipara L, Chaudhari U, Vanhaecke T, Rogiers V, Vinken M et al (2018) Omics-based responses induced by bosen- tan in human hepatoma HepaRG cell ...