To present a unique case where detection of oligoclonal bands in serum led to the diagnosis of human immunodeficiency virus (HIV) infection.A 64-year-old man treated for hypertension for 11 years had laboratory tests ordered by his primary care physician, including serum protein electrophoresis (...
OligoclonalBands in CerebrospinalFluids : Significanceof CorrespondingBands in Serum for Diagnosisof MultipleSclerosis 来自 Semantic Scholar 喜欢 0 阅读量: 5 作者:R Davenport,Keren 摘要: Tumor Diagnostic 1981;2:59-.61. 2. Fleisher M, BesenflederE, Oettgen H, Schwartz M. Comparison of ...
3.4.3Oligoclonal bands Oligoclonal bandsare defined by several, at least two discrete immunoglobulin peaks that migrate closely together during electrophoresis and they appear as narrowly placed peaks on the electrophoretogram. These are most common in the gamma-globulin-region. There is no strict ...
established five classical patterns in CSF and paired serum samples, being the type 2 and 3 corresponding to the diagnosis of MS (Table 6, Fig. 1). However, they did not mention the cut off for the number of bands detected in CSF by the IEF technique [41]. It is not until the ...
Oligoclonal immunoglobulins in subacute sclerosing panencephalitis and multiple sclerosis: a study of idiotypic determinants. Studies have been made of the idiotypic determinants of subacute sclerosing panencephalitis (SSPE) antibodies using rabbit antisera to serum and spinal fluid fractions. Evidence is...
To identify signs of chronic inflammation or previous CNS infection, we investigated serum and cerebrospinal fluid (CSF) from a group of 22 narcoleptic patients and a control group of 22 patients suffering from major depression and looked for the occurrence of oligoclonal bands and significantly elev...
Aim Biomarkers such as autoantibodies, neopterin, and oligoclonal bands (OCBs) are increasingly used for the diagnosis of treatable inflammatory central nervous system (CNS) disorders. We investigated the correlation between the results of OCB testing and clinical diagnoses in a large contemporary cohort...
Oligoclonal bands are a constant, non-modifiable feature of CSF examination in SSPE. We studied CSF oligoclonal IgG banding pattern in a long-surviving SSPE patient treated with serial courses of intrathecal α-IFN. α-IFN administration did not significantly modify the clinical status of the pati...
was demonstrated by testing for oligoclonal bands (isoelectric focusing and immunofixation of IgG parallel in serum and CSF) and by calculation of the IgM, IgA, and IgG index (ratio between CSF and serum immunoglobulin class after correcting for albumin concentrations in the CSF and serum). ...
Rabbits sensitized with whole nervous tissue or myelin basic protein (MBP) plus adjuvant and developing experimental allergic encephalomyelitis (EAE) were studied for the presence of oligoclonal immunoglobulin (Ig) bands in spinal fluid and serum. Samples obtained prior to sensitization and at the time...