3.1.1Oligoclonal bands (OCB) OCBare clonally restrictedIgthat are produced intrathecally by Bcell clonesthat populate theCSFand brain parenchyma in some diseases [72]. As alumbar punctureis usually performed at onset of ADS, the presence orabsenceof OCBs, detected byisoelectric focusing, should ...
Oligoclonal banding of IgG in CSF, blood-brain barrier function, and MRI findings in patients with sarcoidosis, systemic lupus erythematosus, and Behcet's disease involving the nervous system. J Neurol Neurosurg Psychiatry 1995; 58: 548-554....
was demonstrated by testing for oligoclonal bands (isoelectric focusing and immunofixation of IgG parallel in serum and CSF) and by calculation of the IgM, IgA, and IgG index (ratio between CSF and serum immunoglobulin class after correcting for albumin concentrations in the CSF and serum). ...
Rabbits sensitized with whole nervous tissue or myelin basic protein (MBP) plus adjuvant and developing experimental allergic encephalomyelitis (EAE) were studied for the presence of oligoclonal immunoglobulin (Ig) bands in spinal fluid and serum. Samples obtained prior to sensitization and at the time...
We analyzed abnormal protein bands (APB), distinct from the presenting paraprotein, in 550 patients receiving high-dose therapy with autologous hematopoietic cell transplantation at a single institution. Fifty-five patients (10%) had APB, 48 had oligoclonal bands (OB), and 23 had an apparent ...
Key words: Oligoclonal bands/Cerebrospinal fl uid/IgG index/Multiple sclerosis Aims: The aim of this study was to assess the correlation between IgG index values and the number of the oligo-clonal IgG bands (OCB) in the cerebrospinal fl uid (CSF) of patients with multiple sclerosis (MS). ...
10.Pryce, G, Baker, D. Oligoclonal bands in multiple sclerosis; Functional significance and therapeutic implications. Does the specificity matter?Mult Scler Relat Disord2018;25:131–7.https://doi.org/10.1016/j.msard.2018.07.030.Search in Google ScholarPubMed ...
Short communication CNS tumours: oligoclonal immunoglobulin D in cerebrospinal fluid and serum Oligoclonal immunoglobulin D bands were detected by isoelectric focusing in 7 out of 25 unconcentrated cerebrospinal fluid (CSF) samples obtained from pati... M Mavra,J Drulovic,Z Levic,... - 《Acta ...
A peculiar feature of rheumatoid arthritis patients is that they carry clonally expanded CD4+ and CD8+ cells in the peripheral blood. While the distortion of the repertoire of CD8+ cells has been ascribed to the increase of CD8+CD57+ large granular lymphocytes, often detected in these patients...
EBNA1 epitope Pep 3–3 selected by panning with MS brain IgG was recognized by multiple high-density IgG bands in both CSF and serum from representative MS patients. (Fig. 6a). These results suggest that the EBNA1 epitope is reactive to MS intrathecal antibodies corresponding to oligoclonal ...