A 51-year-old woman developed weight gain while receiving olanzapine, and pruritus while receiving ziprasidone [ routes of administration not stated ]. The woman was diagnosed with a severe depressive episode with psychotic symptoms. About 7 weeks later, olanzapine was started at a dose of 5mg ...
If not used immediately, shake the vial vigorously to resuspend the drug prior to administration.DosageAvailable as olanzapine and olanzapine pamoate; dosage expressed in terms of olanzapine.For treatment of psychiatric indications (e.g., psychotic disorders, bipolar disorder, treatment-resistant depressio...
Neuroleptic malignant syndrome (NMS) is reported in association with the administration of antipsychotic drugs (eg, olanzapine); clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic instability (irregularpulseor blood pressure, tachycardia, diap...
Depending upon the desired method of administration, bioadhesive formulations of nanoparticulate olanzapine can be prepared by selecting one or more cationic surface stabilizers that impart bioadhesive properties to the resultant composition. Useful cationic surface stabilizers are described below. ...
Since the early 1990s she had intermittently received antidepressants (clomipramine, milnacipran), antipsychotics (olanzapine and amisulpride [ dosages, routes of administration and duration of treatments not stated ]) and memantine for psychiatric complaints, initially presenting as paranoia and anxiety. ...
Mann S, Chintoh A, Giacca A, Fletcher P, Nobrega J, Hahn M, Remington G (2013) Chronic olanzapine administration in rats: ef- fect of route of administration on weight, food intake and body composition. Pharmacol Biochem Behav 103:717-722...
This study assessed the absorption of each by different routes of administration. Secondarily, the influence of P-glycoprotein (P-gp) genotype was assessed. It was hypothesized that more rapid absorption of the OLZ ODT would occur when administered sublingually versus standard oral administration. A...
The Food and Drug Administration approved intramuscular (IM) olanzapine (OLA) for agitation, but the intravenous (IV) route has potential for faster onset and effect. There are limited data comparing both routes of administration. The purpose of this study was to evaluate safety and efficacy of ...
2 of 19 Pharmaceutics 2022, 14, 2587 2 of 19 may be particularly useful for the pharmaceutical industry since higher drug loads can be used in formulations (up to 60–80% w/w) without compromising the stability of amor- phous drugs [11], or the size amenable to patient administration. ...