Dube SW; Andersen RM;Tohen DC.Onset of action olanzapine-fluxetine combination for bipolar depression.Be havbrain Res.2004.202-205Dube S W, Andersen M, Tohen E. Onset of action olanzapine-fluxetine combination for bipolar depression[J]. Behavbrain Res, 2004,30(7):202...
Olanzapine is active in many animal behavioural models of antipsychotic activity. Inhibition of a number of dopamine and serotonin agonist-induced behaviours was demonstratedin vivo, confirmingin vitroevidence of the receptor affinity profile of olanzapine. In animal models considered predictive of the pot...
Onset of action was generally similar among olanzapine long-acting injection, therapeutic doses of oral olanzapine, and oral haloperidol, based on a mean change in symptoms, and the magnitude of symptom reduction with 3 doses of the long-acting injection was similar to that with 10 to 15 mg...
Olanzapine belongs to a drug class known as atypical antipsychotics. Other members of this class includeclozapine(Clozaril),risperidone(Risperdal),aripiprazole(Abilify) andziprasidone(Geodon). The exact mechanism of action of olanzapine is not known. It may work by blocking receptors for several neuro...
BackgroundTo treat acute schizophrenia, a long-acting antipsychotic formulation needs a rapid onset of action and therapeutic profile similar to that of oral agents. The present analysescompared results from a fixed-dose, randomized, double-blind, placebo-controlled trial of olanzapine long-acting inje...
In an FDA review of 23 cases of DRESS, including 1 fatal case, associated with olanzapine use worldwide, median onset of DRESS symptoms was 19 days after initiation of therapy and median olanzapine dosage was 20 mg daily, although DRESS reported at dosages as low as 5 mg daily. The 22 ...
Side effects of Zyprexa include: akathisia(an inability to sit still), constipation, headache, dizziness, lightheadedness, drowsiness, tiredness, restlessness, weight gain (more likely in teenagers), increased appetite, memory problems, stomach pain or upset, ...
Startle magnitude was defined as the maximum force (measured in Newtons) applied by the rat to the startle apparatus recorded over a period of 100 ms beginning at the onset of the pulse stimulus. Between each stimulus trial, 100 ms of activity was recorded when no stimulus was present....
receiving moderately or highly emetogenic chemotherapy Common side effects of olanzapine when used over a period of months include weight gain as well as an association with the onset of diabetes mellitus, but these effects have not been seen with short term use of daily doses of less than ...
weakness, hypertension, and convulsion. The potential for onset of an event is greatest within the first hour. The majority of cases have occurred within the first 3 hours after injection; however, the event has occurred after 3 hours. Following the 3-hour observation period, healthcare ...