The benefit of maintaining bipolar I patients on monotherapy with oral ZYPREXA at a dose of 5 to 20 mg/day, afterachieving a responder status for an average duration of 2 weeks, was demonstrated in a controlled trial [seeClinical Studies] . The healthcareprovider who elects to use ZYPREXA ...
IM Administration of Short-acting Olanzapine (e.g., Zyprexa IntraMuscular)Short-acting (immediate-release) olanzapine (10 mg per vial) is used for agitation associated with schizophrenia or bipolar mania; do not confuse this formulation with the long-acting olanzapine pamoate formulation (Zyprexa ...
OLZ was better than HAL at 15, 30 and 45 minutes (p # .013) indicating a faster onset of action. Significantly fewer OLZ- and PLA-treated patients required concomitant anticholinergics while fewer OLZ- and HAL-treated patients required concomitant benzodiazepines. EPS (p=.033) and dystonia...
O lanzapine is classed as an atypical antipsychotic and is considered a firstline agent in the management of newly diagnosed psychosis. It has a similar mechanism of action to classical antipsychotics but with a lower incidence of adverse events. O lanzapine rarely produces hypotension and has les...
Intramuscular olanzapine has shown faster onset of action, greater efficacy and fewer adverse effects than haloperidol or lorazepam in the treatment of acute ... J Battaglia - 《Drugs》 被引量: 275发表: 2005年 Calming versus sedative effects of intramuscular olanzapine in agitated patients Distinct ...
IM), is indicated for agitation associatedwith schizophrenia or bipolar I mania. Olanzapine iscombined with fluoxetine (Symbyax) for use in depressionthat is associated with bipolar I disorder. Peak concentrationsof oral olanzapine are reached at 6 hours after oral administration,and absorption of the...
• Lorazepam (IM):Increased somnolence with IM olanzapine. ( 7.2) • Other Concomitant Drug Therapy:When using olanzapine in combination with lithium or valproate, refer to the Drug Interactions sections of the package insert for those products. ( 7.2) Use In Specific Populations • Preg...
weakness, hypertension, and convulsion. The potential for onset of an event is greatest within the first hour. The majority of cases have occurred within the first 3 hours after injection; however, the event has occurred after 3 hours. Following the 3-hour observation period, healthcare ...
Onset of action of antipsychotics in the treatment of mania Introduction: An important consideration in treating acute mania is the promptness with which a chosen therapy can bring symptom amelioration. This articl... M Tohen,TG Jacobs,PD Feldman - 《Bipolar Disorders》 被引量: 12发表: 2015年...
While the efficacy of antipsychotic medications for the treatment of psychosis is generally established, the speed of onset of antipsychotic action remains controversial. The objective of this study was to evaluate the early response (within the first 24 h) in psychosis with ziprasidone IM treatment,...