CONCLUSION: Olanzapine appears to be effective and safe for patients with psychotic depression. Further prospective studies are warranted to ascertain whether olanzapine's unique pharmacologic profile may make it particularly useful for the treatment of psychotic depression either alone or in combination wit...
Smith E, Rothschild AJ, Heo M, Peasley-Miklus C, Caswell M, Papademetriou E, Flint AJ, Mulsant BH, Meyers BS; STOP-PD Collaborative Study Group. Weight gain during olanzapine treatment for psychotic depression: effects of dose and age. Int Clin Psychopharmacol. 2008;23(3):130-137.S...
Olanzapine, mean dose 5.4mg/day, has been given to 21 patients with apathy in theabsenceof depression after long-term treatment withselective serotonin reuptake inhibitorsfor non-psychotic depression in an open, flexible-dose study [16]. The more frequentadverse effectswere sedation (n=12), incre...
JukapunYoodee, ...MantiweeNimworapan, inCritical Reviews in Oncology/Hematology, 2017 Abstract Background Olanzapineis an anti-psychotic drug that has been used for preventing and treating Chemotherapy-Induced Nausea and Vomiting (CINV). This study aimed to systematically review and meta-analyze the...
For treatment of psychiatric indications (e.g., psychotic disorders, bipolar disorder, treatment-resistant depression) in debilitated patients, in those predisposed to hypotension, in those who may be particularly sensitive to the effects of olanzapine, or in those who might metabolize olanzapine ...
Olanzapine is a second-generation anti-psychotic drug used to prevent neuroinflammation in patients with schizophrenia. However, the long-term administration of olanzapine leads to insulin resistance (IR); the mechanisms of this effect remains poorly understood. Using cellular and rodent models of IR ...
. If parenteral benzodiazepines are required for patient management during an event of post-injection delirium/sedation syndrome, careful evaluation of clinical status for excessive sedation and cardiorespiratory depression is recommended. Elderly Patients With Dementia-Related Psychosis...
Combination therapy of olanzapine (zyprexa) and fluoxetine (prozac) for treatment of bipolar disorder The invention provides methods and compositions for the treatment of Bipolar Disorder, Bipolar Depression or Unipolar Depression, all with or without psychotic features. This method employs a compound hav...
High rates of attrition have been reported in randomized controlled trials of patients with severe psychiatric illness, including psychotic depression (MDp... J Weissman,A Flint,B Meyers,... - 《Psychiatry Research》 被引量: 88发表: 2012年 加载更多来源...
Impaired neural synchronization is a hallmark of psychotic conditions such as schizophrenia. It has been proposed that schizophrenia-related cognitive deficits are caused by an unbalance of reciprocal inhibitory and stimulatory signaling. This supposedly