A 50-year old woman developed oedema in her hands and ankles during treatment with olanzapine for bipolar II disorder. The woman, who had a history of recurrent depression and a remote history of transient oedema of unknown origin, developed bilateral oedema in her hands and ankles 2 days ...
Olanzapine (brand name Zyprexa) is an atypical antipsychotic that may be used to treat adults and adolescents aged 13 and older with schizophrenia or bipolar I disorder. For bipolar I disorder, it may be used alone for manic or mixed episodes; or in comb
Usual Adult Dose for Bipolar DisorderMonotherapy:Initial dose: 10 or 15 mg orally once a day Dose adjustments: If indicated, dose adjustments should occur at intervals of at least 24 hours in 5 mg increments/decrements. Maintenance dose: 5 to 20 mg orally once a day Maximum dose: 20 mg/...
Olanzapine monotherapy is effective in the acute treatment of bipolar depression, with a safety profile similar to that already known for the antipsychotic, new research shows. Mauricio Tohen, MD, DrPH, University of Texas Health Science Center at San Antonio, and colleagues found that a largely ...
The benefit of maintaining bipolar I patients on monotherapy with oral ZYPREXA at a dose of 5 to 20 mg/day, afterachieving a responder status for an average duration of 2 weeks, was demonstrated in a controlled trial [seeClinical Studies] . The healthcareprovider who elects to use ZYPREXA ...
Bipolar disorder Olanzapine may also be used for other conditions as determined by your healthcare provider. How does olanzapine work (mechanism of action)? Olanzapine belongs to a group of medicines called second-generation (atypical) antipsychotics. It is thought to work by balancing brain chemical...
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study blind study compared flexibly dosed olanzapine (5-20 mg/day) to divalproex (500-2500 mg/day) for manic or mixed episodes of bipolar disorder (N=251)......
Bipolar depression: a new role for atypical antipsychotics? Bipolar depression, the most common phase of bipolar disorder, causes significant morbidity and mortality. Traditional drugs such as lithium, lamotrigine o... PE Keck - 《Bipolar Disorders》 被引量: 3发表: 2015年 Is it depression or is...
The benefit of maintaining bipolar I patients on monotherapy with oral ZYPREXA at a dose of 5 to 20 mg/day, afterachieving a responder status for an average duration of 2 weeks, was demonstrated in a controlled trial [seeClinical Studies] . The healthcareprovider who elects to use ZYPREXA ...
1.2 Bipolar I Disorder (Manic or Mixed Episodes) Monotherapy— Olanzapine orally disintegrating tablets are indicated for the acute treatment of manic or mixed episodes associated with bipolar I disorder and maintenance treatment of bipolar I disorder. Efficacy was established in three clinical trials in...