17、Anothernucleic acid, RNA, carries the information to a molecular machine called a ribosome, which reads the RNA and strings together amino acids to form the protein.(另一种被称之为rna的核酸负责将信息传递到名为核糖体的分子机器上,核糖体通过阅读RNA信息,并将氨基酸串联起来形成蛋白质。) 18、Th...
To overcome these challenges, various delivery approaches and formulations were used to optimize the efficacy and safety profiles of nucleic-acid-based drugs such as virus-mediated delivery, lipid-mediated delivery, polymer-mediated delivery, and physical delivery methods. Among these, polymer-basednanoca...
A polymer compound selected from a homopolymer of (a) and a block copolymer of (b). (a) A homopolymer comprising a polyether segment having a side chain including a primary amine. (b) A block copolymer of a polyether segment having a side chain including a primary amine, and a poly(...
If deoxy-ribonucleotides are used, the polymer is called deoxyribonucleic acid, or DNA. If ribonucleotides are used, the polymer is called ribonucleic acid, RNA. 核苷酸聚合起来产生的就是核酸。如果使用的是脱氧核糖核苷酸,产生的聚合物是脱氧核糖核酸,简称为DNA。如果使用的是核糖核苷酸,产生的聚合物是...
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are molecular hallmarks of life on Earth. They are constructed of relatively simple organic constituents called nucleosides, which are linked by 3ʹ,5ʹ-phosphodiester bonds to form single oligonucleotide strands. These strands can, in t...
Life on Earth only exists thanks to a class of organic compounds called nucleic acids. This classification of compounds consists of polymers constructed from nucleotides. Among the best-known nucleic acids include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). DNA provides the blueprint of...
, usually single-stranded chain of alternating phosphate and ribose units, with one of the bases adenine, guanine, cytosine, or uracil bonded to each ribose molecule. RNA molecules are involved in protein synthesis and sometimes in the transmission of genetic information. Also calledribonucleic acid...
The present invention relates to a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a tumour antigen or a fragmen
Figure 5.17.Structure of Peptide Nucleic Acid Compared to DNA A) The PNA polypeptide backbone. B) The sugar and phosphate backbone of normal DNA. B=nucleic acid base. The brackets with “n” indicate a polymer with multiple repeats.
Arginine grafted bio-reducible polymer hMSC: Human mesenchymal stem cell CMC: Critical micelle concentration PM: Polyplex micelles CA-CSO-SA: Cis-aconitate-modified chitosan-g-stearic acid AA–AuNPs: Amino acid-functionalized gold nanoparticles ...