The spatial distribution of glycosylated RNAs in single cells can be imaged using a protocol that uses an aptamer and a DNA probe that are specific for sialic acid-containing glycosylated RNAs. It can be applied to imaging other glycosylated RNAs using aptamers for other glycans. ...
Nucleic acids—our buddies deoxyribonucleic acid, or DNA, and ribonucleic acid, or RNA—consist of long chains of nucleotides, which are monomers. (Sensing a pattern yet? Good. Biology is all about patterns.)Every nucleotide has three parts: A sugar A phosphate group A nitrogen-containing ...
Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology. Immunol. Rev. 269: 60-75.Pelka K, Shibata T, Miyake K, ... K Pelka,T Shibata,K Miyake,... - 《Immunological Reviews》 被引量: 17发表: 2016年 The role of Toll-like receptors in immunity again...
Nucleic Acids - Nucleic acids are substances present in living cells. Know about nucleic acid's definition, the function of nucleic acids, DNA & RNA, their composition @BYJU'S.
Topics in Nucleic Acid Structure : Topics in Molecular and Structural Biology; volume 1 edited by S. Neidle General editors: W. Fuller and S. Neidle MacMil... D Shugar - 《Febs Letters》 被引量: 0发表: 1982年 A standard reference frame for the description of nucleic acid base-pair ...
答案 1. DNA polymerase only works in one direction, from 5' to 3', adding new nucleotides to the 3' OH end 2. Since the two parental strands are antiparallel, the leading strand is being synthesized continuously in the direction of the replication fork in 5' to 3' direction by DNA pol...
Nucleic Acid. Symposia of the Society for Experimental Biology. No. I.doi:10.1016/0014-5793(91)80246-YAntioxidantCalciumMitochondriaNonspecific permeabilityPropofolSwellingBHTbutylated hydroxytoluenetBHPt -butylhydroperoxideThe molecular mechanism of the Ca2(+)-induced permeabilization of rat liver mitochondria...
Progress in Nucleic Acid Research and Molecular BiologySinger. B. The chemical effects of nucleic acid alkylation and their relation to mutagenesis and ... B Singer - 《Progress in Nucleic Acid Research & Molecular Biology》 被引量: 356发表: 1975年 Structural analysis of nucleic acid aptamers Cu...
Small interfering ribonucleic acid (siRNA):Since 1958, the central dogma stated that DNA was transcribed into RNA and that RNA (called messenger RNA-mRNA) was translated into protein. The discovery of RNA interference (RNAi) in the early 1990’s revolutionized the modern biology56,57. RNAi refe...
Beneficial mutations revealed modes of nucleic acid recognition not previously observed in natural proteins, highlighting the ability of computational directed evolution to access new molecular functions. Furthermore, the process by which new functions were obtained closely resembles natural evolution and can...