a, Summary of benign breast duct cell types and BC subtypes. The image was created with BioRender.com.b, Sample grid processing method utilized in the study to perform various assays on each tumor sample systematically.c, Summary of data types available for single-cell, single-nucleus and ST ...
We compared virulent and avirulent pea aphid parental genotypes, and their bulk segregant F1 progeny onMedicago truncatulagenotypes carrying or lacking theRAP1(Resistance toAcyrthosiphon pisum1) resistance quantitative trait locus. Differential gene expression analysis of whole body and head samples, in c...
It is important to differentiate acute inflammation from chronic inflammation. Acute inflammation is the first reaction of innate immunity and corresponds to an adaptive response, which restores cell and tissue homeostasis. The inflammatory response typically ends once the thread of damage stops, for exa...
aManhattan plot showing association between morphological traits (n = 246) and rare variant burden in candidate genes (n = 9105). Black dotted line represents thep-value threshold after Bonferroni correction for the number of tested traits and genes (P = 0.05/246x9105, i.e. 2.2...
Once sequestered in vesicles, arsenic is moved for long-term storage to the large central vacuole of the gametophyte through membrane fusion between the vesicle and tonoplast. This proposed mechanism provides a compelling mechanism that would allow P. vittata to use PvGAPC1, which has a Km for ...
To accomplish this goal, the author demonstrated that plasmids carrying the EBV sequences and large fragments of human DNA could support long-term autonomous replication in hamster cells, which are not permissive for EBV replication. «less 展开 ...
Long-term culture of alveolospheres This paper GEO (GSE137799) Experimental Models: Cell Lines Human: Normal donor iPSC line targeted with NKX2-1GFP SFTPCtdTomato (BU3 NGST) Kotton Lab (Jacob et al., 2017) http://www.bu.edu/dbin/stemcells/ Human: Donor iPSC line targeted with SFTPCt...
Further on, the efficiency of oxidative phosphorylation (OXPHOS) was evaluated in term of P/O value, calculated as the ratio between ATP synthesis (ATP-synth) and oxygen consumption rate (OCR). These parameters were evaluated in the presence of pyruvate + malate (Pyr + Mal) or succ...
(FFPE) samples. Hence we developed a locked nucleic acid (LNA)-based probe against sncRNA-U14 to be utilized in fluorescence-in-situ-hybridization (FISH) and analyzed panels of in vivo FFPE human tissue biopsies. To start with, we tested the efficiency of detection of sncRNA-U14 in FFPE-...
Previous studies have shown that depletion of cohesin or CTCF leads to misregulation of genes, with fewer transcriptional changes seen following acute and partial depletions, and complete or long-term loss causing hundreds of misexpressed genes (Dowen et al., 2013, Ing-Simmons et al., 2015, ...