Model Description 通过随机转基因方式,将pCMV-hIL34-pA整合到小鼠染色体。 *Literature published using this strain should indicate: CMV-hIL34-Tg(M-NSG) mice (Cat. NO. NM-TG-220433) were purchased from Shanghai Model Organisms Center, Inc.. Validation Data Fig1. Detection of hIL34 expression...
RESEARCH ARTICLE NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice a11111 Madhavi Puchalapalli1¤a, Xianke Zeng1, Liang Mu1, Aubree Anderson1, Laura Hix Glickman2¤b, Ming Zhang2, Megan R. Sayyad3, Sierra Mosticone ...
应用领域:免疫及造血系统研究,肿瘤或细胞移植等。 *使用本品系发表的文献需注明: M-NSG mice (Cat. NO. NM-NSG-001) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 表型分析 T、B、NK 细胞 FACS 检测 图1.M-NSG 小鼠脾脏中 T、B 和 NK 细胞缺失。取 BALB/c、NOD-scid 和 M...
*使用本品系发表的文献需注明: B2m-KO(M-NSG) mice (Cat. NO. NM-NSG-002) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig 1. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice. ...
*Literature published using this strain should indicate: M-NSG mice (Cat. NO. NM-NSG-001) were purchased from Shanghai Model Organisms Center, Inc.. Validation Data 表型分析 T、B、NK 细胞 FACS 检测 图1.M-NSG 小鼠脾脏中 T、B 和 NK 细胞缺失。取 BALB/c、NOD-scid 和 M-NSG 小鼠的脾脏...
NSG mice provide an ideal model for monitoring host responses to the infection and for testing parasites in vivo for susceptibility to direct chemotherapeutic activity of new agents.doi:10.1038/s41598-023-27537-zJessica A. Hessgrid.265008.90000 0001 2166 5843Department of Microbiology and Immunology,...
This data demonstrates that NSG mice provide a better model for studying human breast cancer metastasis compared to the current nude mouse model. 展开 关键词: METASTATIC breast cancer CANCER-related mortality CANCER cells TUMOR growth LABORATORY mice ...
由南模生物自主研发,该品系在 NOD-SCID 的基础上敲除 Il2rg 基因,是一种严重免疫缺陷小鼠,缺失成熟T、B、NK细胞,是人源化小鼠、异种移植、免疫重建的重要载体;对于研究人类造血干细胞、肿瘤发生与治疗、免疫缺陷疾病与体内免疫机制研究都具有重要意义。 该小鼠详细信息及验证数据请点击:https://www.modelorg.com/...
3D) of knock-in mice but not in WT-NSG littermates. Together, we successfully generated the hCD147KIhet-NSG mouse model, which can be used to test SARS-CoV-2 infection in vivo. Surface expression of the human CD147 protein was thus verified in PBMCs, Lung, Liver, and Spleen. Fig....
Body weight growth curve and GvHD scores of huPBMC-M-NSG-hIL4 mice Flow analysis of peripheral blood lymphocyte subpopulations in the huPBMC-M-NSG-hIL4 model hIL4-Tg(M-NSG)小鼠尾静脉注射人源PBMC(1E7),并在注射后3-4周取外周血进行流式检测分析。 结果显示:huPBMC-M-NSG-hIL4小鼠模型GvHD症...