JAX humanized NOD scid gamma (Hu-NSG) mice are engrafted with cord blood-derived CD34+ HSC and have shown robust T cell reconstitution. In this report we evaluated two novel BiTEs, EGFR-CD3 and BCMA-CD3, in Hu-NSG mice implanted with MDA-MB-231 human breast cancer cells and NCI-H929...
英文名称: NSG-SGM3 总访问: 5527 国产/进口: 进口 半年访问: 299 产地/品牌: 杰克森实验室(JAX) 产品类别: 实验动物 规格: NSG-SGM3 最后更新: 2025-4-5 货号: 013062 参考报价: 询价议价 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:微信新浪微博销售商: ...
marginally sensitive to SARS-CoV-2 infection compared to WT-NSG littermates characterized by increased viral copies by qRT-PCR and moderate body weight decline compared to baseline; (3) a significant increase in leukocytes in the lungs of hCD147KI-NSG mice, compared to infected WT-NSG mice....
NSG mice are widely used for the transplantation of human peripheral blood immune cells (PBMC) [40]. We considered that the absence of Neu5Gc and human-like sialylation of glycoproteins could change the behavior of mature human immune cells derived from the adult donor. PBMC isolated from one ...
将转基因显微注射到受精的 NSG 卵母细胞中(品系货号 005557 https://www.jax.org/strain/005557)。将获得的首建鼠与 NSG 杂交,此后该品系在 NSG 背景下维系。 点击此链接下载NSG™ 系列小鼠比较对照表: https://www.jax.org/jax-mice-and-services/customer-support/manuals-posters-and-guides/jmcrs-...
To enhance NK cell development, we have developed NSG mice that constitutively expresses human IL15 using a BAC containing the human IL15 gene: NSG-Tg(Hu-IL15) (NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(IL15)1Sz/SzJ; JAX stock number 030890). NSG-Tg(Hu-IL15) mice express a physiological ...
marginally sensitive to SARS-CoV-2 infection compared to WT-NSG littermates characterized by increased viral copies by qRT-PCR and moderate body weight decline compared to baseline; (3) a significant increase in leukocytes in the lungs of hCD147KI-NSG mice, compared to infected WT-NSG mice....
https://www.jax.org/jax-mice-and-services/customer-support/technical-support/breeding-and-husbandry-support/mouse-identification 品系建立 三重突变小鼠是将 NOD/LtSz-Prkdcscid B2mtm1Unc/Sz(品系货号 003449)小鼠与 NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz(品系货号 005557)小鼠交配繁育获得。将获得的小鼠雌雄交...
RRID:IMSR_JAX:014570 通用名称:NSG-HLA-A2/HHD NSG-HLA-A2/HHD 突变小鼠具有免疫缺陷并表达人I 类HLA重链和轻链。此品系可作为人造血细胞移植的宿主,当植入人造血干细胞时,支持人 T 细胞的成熟。 如需订购植入CD34+ 或 PBMC 的此模型,请访问“人源化小鼠”页面。 https://www.jax.org/jax-mice-and-ser...
The NSG-SGM3 mice (NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG) 1Eav/MloySzJ, JAX stock #013062) were obtained from The Jackson Laboratory (Bar Harbor, ME, USA). This strain was originally described in Wunderlich et al., 2010 [66] and Billerbeck et al., 2011 [67]. Bo...