虽说如此,依然无法赢得抗肺癌的硬仗,需要有更多、更新、更厉害的手段。 Pie chart showing incidences of non-small cell lung cancers as compared to small cell carcinoma shown at right, with fractions of smokers versus non-s...
Pie chart indicates the proportion of samples which are antipated as responsive to immunotherapy. R Responder, NR Non-responder. b Comparison of specific immune cell subtypes among different patients. Kruskal-Wallis test was used to testify the difference among patients. Centre dots represent the ...
Fig. 3. Bar chart side by side comparison of pre-clinical IC50 between brigatinib and lorlatinib against four different crizotinib-resistance mutations (G1202R [3A], G1202del [3B], L1198F [3C], G1269A [3D]) [15]. 2.7. Retrospective institutional analysis of differential response to AL...
(A) Representation of the on-target and off-target mechanisms; (B) pie chart depicting the different percentages of each resistance mechanism. Abbreviations: KRAS = Kirsten rat sarcoma virus gene; EGFR = Epidermal Growth Factor Receptor; HER2 = human epidermal growth factor receptor 2; ALK = ...
Figure 1. Flow chart of data collection and analysis. Table 1. Clinical characteristics of the patients involved in the study. 3.2. Genetic Variations of Ferroptosis-Related Genes in LUAD and LUSCC Patients CNVs, somatic mutations and expression levels of 57 ferroptosis-related genes were summa...
last 15 years [3]. First-line platinum-doublet chemotherapy had been the standard of care until 2005; however, since then, there has been the addition of maintenance pemetrexed in patients with non-squamous histology, the identification and targeting of driver mutations, and immunotherapy [4,5,...