Rath, C. M., Scaglione, J. B., Kittendorf, J. D., Sherman, D. H., Lew, M., and Hung- Wen, L. (2010) NRPS/PKS Hybrid Enzymes and Their Natural Products, in Comprehensive Natural Products II, Elsevier, OxfordRath CM, Scaglione JB, Kittendorf JD, Sherman DH. NRPS/PKS hybrid...
Fungal hybrid enzymes consisting of a polyketide synthase (PKS) and a nonribosomal peptide synthetase (NRPS) module are involved in the biosynthesis of a vast array of ecologically and medicinally relevant natural products. Whereas a dozen gene clusters could be assigned to the requisite PKS–NRPS ...
TeA is thought to be a hybrid of an isoleucine and two acetates12. Due to its tetramic acid-containing structure (Fig. 1a), TeA is also expected to be a product of a polyketide synthase and non-ribosomal peptide synthetase (PKS–NRPS) hybrid enzyme13. Typical fungal secondary metabolite ...
2013. Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining. Chembiochem 14:2095-2099. http://dx.doi.org/... WI Abe - 《Chembiochem A European Journal of Chemical Biology》 被引量: 0发表: 2013年 Genomics-driven discovery of PKS-NRPS hybrid metabolit...
Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining . Chembiochem 14 :2095–2099. doi:.10.1002/cbic.201300430 [ Cross Ref ]T. Awakawa, X. L. Yang, T. Wakimoto and I. Abe, ChemBioChem , 2013, 14 , 2095–2099 ....
Considering the reported biosynthetic pathway of naringenin and the substrate promiscuity of the A domains in NRPS-PKS hybrids21, we proposed that FnsA might recognize p-CA (3) or simple molecules such as free or protein-bound amino acids as substrates for the biosynthesis of 1. To confirm ...
biosynthesis of amino acid derived pyrones by an nrps nrpks hybrid megasynthetase in fungi 来自 ACS 喜欢 0 阅读量: 9 作者: yanghai 摘要: Fig. S20. HMBC NMR spectrum of desacetyl-pyrophen (5) formate salt in (CD3)2SO (500 MHz). ...37 Fig. S21. 1H NMR spectrum of Boc-desmethyl-...
Functional analysis of non-ribosomal peptide synthetases (NRPSs) in Trichoderma virens reveals a polyketide synthase (PKS)/NRPS hybrid enzyme involved in t... Trichoderma virens genome harbours genes encoding 22 non-ribosomal peptide synthetases (NRPSs) with at least one complete module (containing ...
ANALYZE HYBRID NRPS/PKS SEQUENCES 可进入 化合物快速分析界面,通过序列比对分析未知氨基酸 序列。点击 NRPSDB、PKSDB、ITERDB 和 CHSDB 链 接,分别进入相应子数据库界面[18]。 NRPSDB NRPSDB 数据库搜集了 17 个 NRP 簇和 5 个杂合 · 282 ·
The ring structure of pyridomycin was generated by the nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) hybrid system (PyrE-PyrF-PyrG)... T Huang,Z Zhou,M Wei,... - 《Applied & Environmental Microbiology》 被引量: 0发表: 2022年 加载更多来源...