This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor tha
Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] 基因名: NR3C2 别名: MR,MCR,MLR,NR3C2VIT 基因ID: 4306 Chromosome:(GRCh37) 4 Start: 148999915...
Aggressive behavior is a multifactorial disease, and the etiology is largely unknown. The stress-related hypothalamic-pituitary-adrenal (HPA) axis is a crucial system in the stress response that has emerged as a potential mechanism of aggressive behavior. The NR3C2 gene is an important regulator ...
Ensembl Gene IDENSG00000151623.15 Ensembl mRNA IDNR3C2-203 包装清单: 产品编号产品名称包装 QH04225SHuman NR3C2 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
The NR3C2 gene, encoding the mineralocorticoid receptor (MR), harbors over 380 rare coding variants that significantly influence mineralocorticoid homeostasis and disease susceptibility. These variants include both loss-of-function mutations linked to renal pseudohypoaldosteronism type 1 and gain-of-...
北京索莱宝科技有限公司生产的Anti-NR3C2 Polyclonal Antibody,最新报价:960.00元/ul,背景资料Thisgeneencodesthemineralocorticoidreceptor,whichmediatesaldosteroneactionso
(MR) and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain MR. The corresponding gene for the mineralocorticoid ...
Entrez Gene:4306 Swiss Prot:P08235 Source:KLH conjugated synthetic peptide derived from human Mineralocorticoid receptor:601-700/984 Purification:affinity purified by Protein A Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one...
HeLa cells were transfected with gene-specific siRNA before infecting with HSV-1-eGFP (MOI 0.5). Replication was monitored as a function of GFP fluorescence, and the slopes of replication during the linear phase were calculated, normalized to controls (average of mock and RSCF-transfected cells)...
Swiss ProtP08235 Gene SymbolNR3C2 ELISA TypeSandwich ELISA DataQuantitative Sample TypeSerum, plasma, tissue homogenates, cell culture supernates and otherbiological fluids. AvailabilityShipped within 5-12 working days. NoteThis product is for research use only. The range and sensitivity is subject ...