and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation...
Gene ID: 2908 种属 Homo sapiens 基因序列编号: NM_000176.3 基因描述 Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 1, mRNA DNA编码区: atggactccaaagaatcattaactcctggtagagaagaaaaccccagcagtgtgcttgct caggagaggggagatgtgatggacttctataaaaccctaagaggaggagctactgtga...
NR3C1 gene on the other hand were analyzed by the String database. Results The NR3C1 expression in ccRCC tissue was statistically different from that in normal renal tissue (P＜0.05). The overall survival rate of the patients with a high NR3C1 expression was significantly higher than that of...
(FRAP). NR3C1 protein and Mediator promoted SE-related gene transcription via phase separation. SEs and NR3C1 co-binding patterns were explored using Cleavage Under Targets and Tagmentation (CUT&Tag) sequencing. 5-FU-related ...
Gene ID (NCBI) 2908 Alternative Names GCCR;GCR;GCRST;GR;GRL Application Notes: The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of variou...
NR3C1 gene variation may be associated with GC resistance in PV patients. More extensive genetic analyses and mechanistic analysis are required for further exploration.doi:10.1038/s41598-017-12255-0Fang, Si-YueLi, Chun-LeiLiu, Xiao-SongChen, Feng...
Rats raised by inattentive mothers had greater methylation of the NR3C1 gene. Counselors' Neuroscience Conceptualizations of Depression Some asthmatics even experienced worsened symptoms after corticosteroid treatment.[3] Studies have revealed that several genes, such as NR3C1 ,[4] STIP1 ,[5] CRHR1 ...
Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance. Studies have shown that glucocorticoid receptor (GR) must be associated with a complex of chaperone proteins for ligand activation. GR binds to known steroids such as dexamethasone with ...
and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or ...