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Accessing the massive amount of breast cancer data that are currently publicly available may seem daunting to the brand new graduate student embarking on his/her first project or even to the seasoned lab leader, who may wish to explore a new avenue of in
Triple negative breast cancer (TNBC), which accounts for 15–20% of incident breast cancers, is the only breast cancer (BC) subtype that lacks targeted treatments. Using clinical assays, TNBC is human epidermal growth factor receptor 2 (HER2) negative and has <1% expression of estrogen receptor...
We assessed the PREDICT v 2.2 for prognosis of breast cancer patients with pathogenic germline BRCA1 and BRCA2 variants, using follow-up data from 5453 BRCA1/2 carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and the Breast C
npj Breast Cancer publishes original research articles, reviews, brief communications, matters arising, meeting reports and hypothesis generating observations which could be unexplained or preliminary findings from experiments, novel ideas, or the framing of new questions that need to be solved. Featured ...
20.Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer 机译:Honeybee Venom和Melittin抑制了Her2浓缩和三阴性乳腺癌中生长因子受体激活 作者:Ciara Duffy;Anabel Sorolla;Edina Wang;Emily Golden;Eleanor Woodward;Kathleen Davern;Diwei Ho;Elizab...
prevention and/or treatment tailored specifically to the individual patient based on the genetic and/or molecular profile of the patient. High-impact articles that entail relevant studies using panomics, molecular, cellular and/or targeted approaches in the cancer research field are considered for publi...
Fig. 1: Intrinsic molecular subtypes of breast cancer. Within each clinical subtype there are multiple molecular subtypes. ER endocrine receptor; TNBC triple negative breast cancer; HER2 Human Epidermal Growth Factor Receptor 2. Full size image ...
In breast cancer, nerve presence has been correlated with more invasive disease and worse prognosis, yet the mechanisms by which different types of peripheral nerves drive tumor progression remain poorly understood. In this study, we identified sensory n
It is largely unknown how the development of breast cancer (BC) is transduced by somatic genetic alterations in the benign breast. Since benign breast disease is an established risk factor for BC, we established a case-control study of women with a histo