Basal insulin peglispro (BIL) has a longer duration of action than conventional insulin analogues and a hepato-preferential mechanism of action. This study assessed whether BIL was non-inferior to isophane insulin (NPH) in reducing HbA1c in insulin-na茂ve patients with type 2 diabetes, when ...
OBJECTIVE -- Insulin detemir is a soluble basal insulin analog with a unique mechanism of protracted action designed to reduce the variability associated w... Vague,Philippe,Selam,... - 《Diabetes Care》 被引量: 328发表: 2003年 Insulin detemir compared with NPH insulin in children and adolescen...
insulin‐naïvetype2diabetesBasal insulin peglispro (BIL) has a longer duration of action than conventional insulin analogues and a hepato‐preferential mechanism of action. This study assessed whether BIL was non‐inferior to isophane insulin (NPH) in reducing HbA1c in insulin‐naïve patients...
To fully explain this subtle difference in the relative effects of insulin detemir and NPH insulin on weight as a function of BMI observed in these two studies, some insight into the mechanism, or mechanisms, by which insulin detemir exerts its weight-sparing effect will likely be required. The...
OBJECTIVE -- Insulin detemir is a soluble basal insulin analog with a unique mechanism of protracted action designed to reduce the variability associated with conventional basal insulins. This trial compared the glycemic control, risk of hypoglycemia, and effect on body weight of insulin detemir and...