The most common side effects of MIPLYFFA in patients also taking miglustat include upper respiratory tract infection, diarrhea and decreased weight. These are not all the possible side effects of MIPLYFFA. Call your HCP for medical advice about side effects. You are encouraged to report side ef...
In this form of disease, the internal organs are the most affected30. Patients can present in-utero splenomegaly, in-utero hepatomegaly, in-utero ascites, and intrauterine growth retardation36. Placentomegaly has also been reported36. After birth, symptoms include congenital thrombocytopenia, congen...
5. Twelve years – I am still healthy and full of energy (colon-liver cancer) Let me make my own decision: No chemo for me! (ovarian cancer) I want to be beautiful when I die. But with herbs and good diet I am still alive and healthy (breast cancer) Thank you for sharing and ...
Full size image We next took advantage of brain-wide imaging in the zebrafish model to investigate potential regional differences in the microglial phenotype. This revealed that compared to ameboid microglia found in the optic tectum (OT), microglia in the adjacent hindbrain (HB) maintained their ...
When giving CBD oil to your pet, you’ll want to ensure it’s of the highest quality. That means choosing full-spectrum CBD oil over isolate or broad-spectrum options. Full-spectrum CBD contains a wide range of cannabinoids, terpenes, and other helpful compounds that work synergistically to ...
Following is the full text of the Report on the Work of the Standing Committee of the National People's Congress (NPC), which was delivered by Chairman Zhang Dejiang of the NPC Standing Committee on March 8, 2017 for deliberation at the Fifth Session of
Full size image Findings in AD models revealed that under pathological conditions microglia can switch from a resting homeostatic to a DAM state that is characterized by distinct transcriptomic signatures37,63. We profiled the proteome of cerebral microglia acutely isolated from 8 weeks old Npc1−...
Because the proportion of Hispanics residing in many parts of the study area was low, Hispanic ethnicity was frequently not noted in the medical record (e.g., the hospital intake form did not include an ethnicity check-off ). Patients were categorized as non-Hispanic unless there was evidence...
Full size image Inhibition of NPC1 represses the migration and invasion ability of liver cancer The crucial role of the epithelial-mesenchymal transition (EMT) in tumor cell invasion and metastasis has been widely recognized. Initially, we used the GSCA online database developed by Professor Guo An...
Full size image BAs can enter the enterocytes via passive diffusion or apical sodium-dependent bile acid transporter (ASBT). Passive diffusion mediates the entry of unconjugated BAs in the jejunum32, even the passive permeability of CDCA in the jejunum is 9-fold that in the ileum33. ASBT is ...