近日，Nature杂志背靠背在线发表了两篇NP137抗肿瘤分子机制的研究论文，分别是来自法国里昂大学的Patrick Mehlen团队和法国Netris Pharma公司Agnes Bernet团队合作的论文 Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer 以及比利时布鲁塞尔自由大学Cedric Blanpain团队联合法国Netris Pharma公司A...
近日,Nature杂志背靠背在线发表了两篇NP137抗肿瘤分子机制的研究论文,分别是来自法国里昂大学的Patrick Mehlen团队和法国Netris Pharma公司Agnes Bernet团队合作的论文Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer以及比利时布鲁塞尔自由大学Cedric Blanpain团队联合法国Netris Pharma公司Agnes ...
In preclinical studies, targeting netrin-1 with the humanized anti-netrin-1 antibody NP137 inhibits tumor growth and metastasis. Methods Adults with advanced, refractory solid tumors received NP137 IV Q2W, starting at 1mg/kg. Dose was escalated using a rapid titration design followed by a model...
368 NP137, the first humanized monoclonal antibody directed against netrin-1, exhibits antitumor activity by inducing dependence receptors-mediated cell death 368 NP137, the first humanized monoclonal antibody directed against netrin-1, exhibits antitumor activity by inducing dependence receptors-mediated ...
368 NP137, the first humanized monoclonal antibody directed against netrin-1, exhibits antitumor activity by inducing dependence receptors-mediated cell death - European Journal of Cancerdoi:10.1016/S0959-8049(14)70494-0Delcros, J.G.Ducarouge, B....
摘要: 368 NP137, the first humanized monoclonal antibody directed against netrin-1, exhibits antitumor activity by inducing dependence receptors-mediated cell death - European Journal of CancerDOI: 10.1016/S0959-8049(14)70494-0 年份: 2014