Netrin-1 was first identified as a guidance factor in axon outgrowth during central nervous system development and was later shown to be involved in the morphogenesis of other organs. This study, thus, aimed to verify netrin-1 gene expression in swine antral follicles and to detect netrin-1 ...
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of
0ncogene2004 ;23 (19):3454-61.[0266] 14. Attwell S, Roskelley C,Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene 2000;19 (33):3811-5.[0267] 15. Paol i P,Giannoni E,Chiarugi P. Anoikis molecular pathways and its role in cancer progression.Biochimica et ...
如果需要筛选Cas9成功诱导双链断裂的细胞,推荐用 netrin-1 HDR质粒(h) (sc-401871-HDR) 共转染。 转染后,基因敲除效率可以用抗体:netrin-1: sc-518135,通过WB, IF或者IHC分析 看到协议线上. 下载 说明书 实验流程 快捷链接 相关产品 基因信息 种属基因名称基因ID染色质位置亚型(mRNA)即位号码蛋白质即位号码OMIM...
方法:利用 ProtParam、Genecards、STRING等数据库对 Netrin-1蛋白的序列同源性、亚细胞定位、理化性质、空间结构及蛋白质相互作用网络及表达谱进行综合分析。结果:人Netrin-1蛋白由 604个氨基酸组成,在进化过程中高度保守,属于 Laminin_N超家族和 NTR_like超家族,是一种亲水、不稳定的分泌蛋白。该蛋白主要二级结构为无...
Background:Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation ...
2.注释亚群 代码语言:javascript 代码运行次数:0 运行 AI代码解释 # 需要自行看图,定细胞亚群: celltype=data.frame(ClusterID=0:9,celltype=0:9)#定义细胞亚群 celltype[celltype$ClusterID%in%c(1,3,4,9),2]='Immune'celltype[celltype$ClusterID%in%c(5),2]='Endothelial'celltype[celltype$ClusterID...
the progression of cancer cells towards a late EMT state and sustained tumour epithelial states. Short hairpin RNA knockdown of netrin-1 and its receptor UNC5B in EPCAM+ tumour cells inhibited EMT in vitro in the absence of stromal cells and regulated a common gene signature that promotes tumou...
Dilution: WB: 1:500-1:2000 IHC: 1:50-1:200 ELISA: 1:40000 Gene Name: NTN1 Protein Name: Netrin-1 Human Gene Id: 9423 Swiss-Prot: O95631 Formulation: Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide Source: Rabbit Purification: The antibody was affinity-purifi...
Specificity Netrin-1 Polyclonal Antibody detects endogenous levels of Netrin-1 protein. Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Gene Name...