All plasma digoxin values from the anuric patients and the normal subjects were far below the lower limit of the therapeutic range of plasma digoxin. There existed no difference between the digoxin values determined in anuric patients and subjects with normal renal function; in both groups there ...
Regression of myocardial hypertrophy is therefore a meaningful therapeutic goal in HFNEF. Three HFNEF trials thus far reported on regression of myocardial hypertrophy. The subanalysis of patients with LVEF >35% included in the V-HeFT reported a significant reduction in LV mass with enalapril (27)...
Therapeutic Drug Low Reference Ranges High Reference Ranges Critical High Values Carbamazepine 4.0 mcg/mL 12.0 mcg/mL ≥ 15.0 mcg/mL Digoxin 0.8 mg/dL 2.0 mg/dL ≥ 2.1 mg/dL Gentamicin Trough: 1.0 mcg/mL Peak: 5.0 mcg/mL Trough: 1.9 mcg/mL Peak: 8.0 mcg/mL Trough: ≥ 2.0...
Further investigation is required to identify the stem cell pool in the lung in relation to expression of ABC transporters. Repairing and replacing lost lung tissue is a research area of promising therapeutic possibilities [150]. ABCA1 The ABCA1 gene is mapped to chromosome 9q31.1. It is the...
As a result of the heterogeneous nature of the pathophysiologic processes and comorbid illnesses in this population, there is a wide range of clinical outcomes. Accordingly, appreciation of the global nature of HFNEF ideally will better inform optimal design for future diagnostic and therapeutic ...
Further investigation is required to identify the stem cell pool in the lung in relation to expression of ABC transporters. Repairing and replacing lost lung tissue is a research area of promising therapeutic possibilities [150]. ABCA1 The ABCA1 gene is mapped to chromosome 9q31.1. It is the...
In this sense, exploring the cellular and molecular mechanisms of kidney fibrosis may offer fresh insights into the progress of new therapeutic strategies for CKD. Emerging evidence has shown that epithelial-mesenchymal transition (EMT) plays a key role in the process of kidney fibrosis [17–19]....