Acta Paediatrica
( 2001 ) Normal CSF neuron-specific enolase and S-100 protein levels in patients with recent non-complicated tonic-clonic seizures . J Neurol Sci 183 : 27 – 31 .Palmio J, Peltola J, Vuorinen P, Laine S, Suhonen J, Keranen T: Normal CSF neuron-specific enolase and S-100 protein ...
et al. Age-dependent changes in brain, CSF, and plasma amyloid β protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21, 372–381 (2001). Article CAS PubMed PubMed Central Google Scholar Iadecola, C. et al. SOD1 rescues cerebral endothelial dysfunction ...
补体可促进中枢神经系统中祖细胞或干细胞的增殖[15],如C5a-C5aR可通过非典型蛋白激酶C(proteinkinaseC,PKC)通路促进胚胎神经细胞增殖,C5aR1敲除后会导致成年小鼠持续的大脑微观结构改变以及行为变化[16]。C3a-C3aR可调节成年小鼠海马脑室下区(subventricularzone,SVZ)和海马齿状回(dentategyrus,DG)的神经发育,C3aR...
This likely represents premyelination changes, such as the appearance of proteolipid protein in oligodendrocyte processes (47). Figure 2-4 (Continued) B-E. Axial T2 FSE images through the cerebrum. Note the complete absence of myelination in the white matter at this age and the smaller ...
Cerebrospinal fluid β-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol 2009;66 (3) 382- 389ArticlePubMedGoogle ScholarCrossref 34. Kapaki EParaskevas GPZalonis IZournas C CSF tau protein and β-amyloid (1-42) in Alzheimer's disease...
We were interested to see whether the protein levels of the apoE4 risk isoform versus apoE3 in plasma could be associated with phenotypical characteristics reported in APOEε4 carriers [11]. Our results indicated that the relative distribution between the risk-isoform apoE4 and the apoE3 isoform...
(TGF-β) level in osteocytes and activation of PTH-PTH receptor signaling cascades in osteoblasts, initiating osteoclast formation20,21(Fig.1.1). In this phase, osteoblasts express monocyte chemoattractant protein-1 (MCP-1), also termed CC motif chemokine ligand 2 (CCL2), receptor activator of...
In primary AML blast cells a deficiency of three JAKs was more common in patients with an abnormal karyotype. In addition, a lack of JAK2 and Tyk2 protein was strongly associated with the FAB M2 phenotype. The proliferation rate in response to GM-CSF available in a small number of patients...
The Thermo matFisher Scientific Pierce BCA Protein Assay Kit (Catalog No. 23225) was used to measure the protein concentration in the tissue lysate samples. The Abcam IgG Human SimpleStep ELISA Kit (Catalog No. ab195215) was used to quantify the concentration of trastuzumab in healthy tissue (...