However, elderly acute myocardial infarction (AMI) patients, a high-risk population themselves, often do not receive the dose of statins recommended by current guidelines because of poor general condition and comorbidities [7]. Moreover, there is limited evidence for using statin therapy in elderly...
A paradigm shift in the cause of atherosclerotic cardiovascular disease (ASCVD) as a “normal” or fundamental part of human aging, is taking place. I put normal in quotes as while it may be a normal aspect of our evolution as a species, that does not mean we don’t want to avoid it...
M. Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nature Rev. Drug Discov. 4, 977–987 (2005). Article CAS Google Scholar Williams, J. P. et al. Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in...
Ionizing radiation can cause substantial tissue degeneration, which may threaten the long-term health of astronauts and radiotherapy patients. To determine ... K Hisataka,ND Searby,M Rose,... - 《Radiation Research》 被引量: 154发表: 2009年 Evaluating the efficacy of statins and ACE-inhibitors...
Professor Baigent said: "We knew from previous trials that statins reduce the risk of heart attacks and strokes in peoplewithnormalkidneyfunction. sharpinfo.org sharpinfo.org Baigent教授说:“既往研究已显示他汀类药物能减少肾功能正常者发生心肌梗死 和中风的风险。
( 2009 ). Effects of statins on vascular endothelial function in hypercholesterolemic patients with type 2 diabetes mellitus: Fluvastatin vs. rosuvastatin ... K Suzumura,K Tanaka,M Yasuhara,... - 《Biological & Pharmaceutical Bulletin》 被引量: 21发表: 2008年 Effects of Low-Dose Atorvastatin...
Impact of atorvastatin or rosuvastatin co-administration on platelet reactivity in patients treated with dual antiplatelet therapy Statins and dual antiplatelet therapy are mandatory in coronary artery disease.Drug–drug interaction could influence suboptimal response to antiplatelet a... M Verdoia,M Nardin...
et al. Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogues and dopastatins. Clin Endocrinol (Oxf) 76, 407–414, doi: 10.1111/j.1365-2265.2011.04200.x (2012). 26. Gruszka, A., Culler, M. D. & Melmed, S. Somatostatin ...
NK cells have been implicated in the pathogenesis of atherosclerosis, so the effect of statin therapy on NK cell cytotoxicity may contribute to the benefits of statins in cardiovascular disease. Introduction HMG-CoA reductase inhibitors (statins) block cholesterol biosynthesis and are widely used in ...
Cocoa beverage and dark chocolate are important dietary sources of polyphenol and have been hypothesised to improve the lipid profile. This systematic review and meta-analysis aimed to investigate the effect of cocoa beverage and dark chocolate intake on