Significantly reduced urinary excretion of total drug (-MD plus digoxin) was shown in patients with CLCR below 50 mL/minute/1.48 m2. This study suggests that the dosage modification is not necessary until CLCR decreases to below 50 mL/minute/ 1.48 m2, but careful attention should be given ...
Home > Section > Chapter Wilson, T.W.; Mahon, W.A.; Inaba, T.; Johnson, G.E.; Kadar, D. Clinical Pharmacology and Therapeutics 14(5): 815-822 1973 ISSN/ISBN:0009-9236 4729899 10.1002/cpt1973145815 042992587 Article emailed within 0-6 h ...
7.2 Digoxin 7.3 Glyburide 7.4 Furosemide 7.5 Nifedipine 7.6 The Use of Metformin with Other Drugs 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.3 Nursing Mothers 8.4 Pediatric Use 8.5 Geriatric Use 10 OVERDOSAGE 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY ...
Simple linear approximate equations for bedside use are presented for various ranges of apparent half-time. In addition, logical extensions of these kinetic relationships permit description of a general dosage formula for smooth replacement of one cardiac glycoside with another that has a different ...