Proliferative capacity and growth curve of cervical epitheliums were evaluated by cell counting kit-8 (CCK-8). The cells at passages 3 were used to infect with HPV-16 E6 gene by lentivirus. The expression of gr
De Sanjosé, SilviaBruni L, Diaz M, Castellsague´ X, Ferrer E, Bosch FX, de Sanjose´ S. Cervical HPV prevalence in five continents: meta-analysis on one million women with normal cytology. J Infect Dis 2010; 202: 1789-1799....
Additionally, various microRNAs exhibit distinct expression patterns between HR-HPV-positive CC cells and HPV-negative CC cells, as well as normal cervical tissues, throughout different stages of the disease. For instance, miR-18a showed increased expression following the suppression of HPV16 and 18 ...
Howell-Jones R, Bailey A, Beddows S, Sargent A, de SN, Wilson G, Anton J, Nichols T, Soldan K, Kitchener H: Multi-site study of HPV type-specific prevalence in women with cervical cancer, intraepithelial neoplasia and normal cytology, in England. Br J Cancer 2010, 103 : 209-216. ...
Objective: Evaluate the prevalence of oral and genital HPV and C.trachomatis infection in women with normal and abnormal cervical cytology. Study design: The cross-sectional study included 200 swabs, 100 oral and 100 cervical from 50 women with normal and 50 with abnormal cervical cytology. HPV ...
RESEARCH ARTICLE Open AccessRisk of cervical lesions in high-risk HPVpositive women with normal cytology: aretrospective single-center study in ChinaZhiling Wang 1 , Ting Liu 1 , Yunjian Wang 2 , Ying Gu 1 , Hui Wang 1 , Jingkang Liu 1 , Baoxia Cui 1 and Xingsheng Yang 1*Abstract...
In vitro models were used to throw light on the multifactorial process of tumor-stroma interaction, by means of studying the cooperation between tumor cells and fibroblasts. Fibroblasts from normal cervix and cervical cancers were grown either separately or in co-culture with CSCC7 cervical cancer ...
(HPV) which is the causative agent of most cervical cancers, expresses oncogenes E7 and E6, deregulates the cell cycle, induces chromosome instability and prevents apoptosis, but is not sufficient to make cells cancerous (Cosper et al.2023). A virus such as herpesvirus, which is a co-...
目的 分析采用宫颈液基细胞学检测、人乳头瘤病毒(HR-HPV)检测、阴道镜检查及宫颈活检术诊断宫颈病变的价值与宫颈病变的临床特点。方法 回顾性分析30例宫颈高度病变(CIN Ⅱ、CIN Ⅲ)患者的临床特点及相关检查结果,所有患者均进行了TCT诊断、HR-HPV检测、电子阴道镜检及宫颈活组织病理学检查。结果 宫颈高度病变患者临床...
Thus, these data generated on an independent set of invasive cervical cancer specimens confirmed p16 and PTGES protein expression as two consistently positive markers to identify HPV-infected cervical cancer cells. Table 4. p16 and PTGES immunostaining in normal cervix keratinocytes and cancer Case...