Normal (MCF12A) and cancer (U251 and HeLa MR) cells exhibit very different metabolic (XTT), proliferative, and cell cycle effects after MNNG exposure.Maithili, Gupte
When MYB is overexpressed or inappropriately activated, some of these, and perhaps additional target genes, contribute to the transforming capacity of MYB. Therapeutic interventions that target MYB in malignancy have been limited, but the observation that ERα+ breast cancer cells have elevated MYB ...
Currently, biomechanics of living cells is in the focus of interest due to noticeable capability of such techniques like atomic force microscopy (AFM) to p... Lekka,Ma?gorzata - 《Bionanoscience》 被引量: 46发表: 2016年 Discrimination Between Normal and Cancerous Cells Using AFM Currently, biom...
as cancer cells have the capacity to modify many homeostatic systems within the body and, consequently, change the production, use and levels of many metabolites17,18. A metabolomic approach may allow for the discovery of biochemical signatures, and, consequently, of differences between...
NORMAL AND CANCER STEM CELLS: DISCOVERY, DIAGNOSIS AND THERAPY INTERNATIONAL SCIENTIFIC CONFERENCE R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv October 5–6, ... E Board - 《Experimental Oncology》 被引量: 0发表: 2017...
and iCORM-2, in the 0.01–100 µM concentration range, cause DNA damage such as strand breaks and alkaline labile sites. DNA damage was repaired efficiently only in HL-60 cells. CORM-2 significantly reduces oxidative stress induced by 1 mM H2O2in normal and cancer cells. On the contrary...
The mechanical features of individual cells have been regarded as unique indicators of their states, which could constantly change in accordance with cellular events and diseases. Particularly, cancer progression was characterized by the disruption and/or reorganization of actin filaments causing mechanical...
Pulsed high-power microwaves do not impair the functions of skin normal and cancer cells in vitro: A short-term biological evaluation Author links open overlay panelSohail Mumtaz a, Pradeep Bhartiya b, Neha Kaushik c, Manish Adhikari b, Pradeep Lamichhane a, Su-Jae Lee c, Nagendra Kumar ...
activity present in almost all cancer cells, but not in normal cells, and the validity of the assay was confirmed with secondary tumor-specific markers... Jay,F.,Dorsey,... - 《Cancer》 被引量: 64发表: 2014年 Methylation-Specific Oligonucleotide Microarray: A New Potential for High-Throughpu...
DNA damage was repaired efficiently only in HL-60 cells. CORM-2 significantly reduces oxidative stress induced by 1mM HOin normal and cancer cells. On the contrary, iCORM-2 in HL-60 cells increases the level of free radicals in the presence of 1 and 5mM HO. We also revealed that both ...