Based on the non-targeted metabolomics, 100 differential metabolites were upregulated in the tea leaves from intercropping system relative to monoculture system. Twenty-one amino acids were upregulated and three downregulated in response to the intercropping based on the targeted metabolomics; half of ...
In the current study, BPs-induced toxicity in HepG2 cells were investigated using an approach integrating LC-MS-based global metabolomics and extracellular flux analysis. Comparing exposure of three BPs at the same dosage level, BPB induced the highest number of dysregulated metabolites and metabolic...
Non-targetedmetabolomicsanalysisrevealsdynamicchangesofvolatile andnon-volatilemetabolitesduringoolongteamanufacture SiChena,b,1,HuihuiLiua,b,1,XiaomanZhaoa,b,XinleiLia,WennaShana,b,XiaxiaWangb, ShanshanWangb,WenquanYuc,ZhenbiaoYangb,d,⁎,XiaominYub,⁎ aCollegeofHorticulture,FujianAgricultureandForestryUn...
Oolong tea is a partially fermented tea with distinct tastes and aromas. However, the dynamic biochemical changes during oolong tea processing are not well understood. In this study, we performed metabolomics-based profiling of non-volatile and volatile constituents of oolong tea during its entire pr...
- 《Metabolomics》 被引量: 306发表: 2008年 On the metabolism of phenylalanine and tyrosine. By labelling phenylalanine with C14 in the benzene ring and C13 in the α-carbon atom, and tyrosine with C14 in theβ-position, it was demonstrated that th... AB Lerner - 《Journal of Biological ...
In addition, we observed large variation in ion abundance within and between the identified saliva metabolites in dog and human.Conclusion The results suggest that non-targeted metabolomics approach utilizing UHPLC-qTOF-MS can detect a wide range of small compounds in dog and human saliva with ...
MetabolomicsPredictive markersOur objective was to identify metabolites associated with fetal growth restriction (FGR) by examining early and late pregnancy differences in non-targeted urinary metabolites among FGR cases and non-FGR controls. An exploratory case-control study within LIFECODES birth cohort ...
Better risk prediction and new molecular targets are key priorities in type 2 diabetes (T2D) research. Little is known about the role of the urine metabolome in predicting the risk of T2D. We aimed to use non-targeted urine metabolomics to discover biomarkers and improve risk prediction for T2D...
Non-targeted metabolomics is the hypothesis generating, global unbiased analysis of all the small-molecule metabolites present within a biological system, ... S Naz,M Vallejo,A García,... - 《Journal of Chromatography A》 被引量: 115发表: 2014年 Targeted and Non-Targeted Approaches for Complex...
Additionally, the non-targeted metabolomics approach was employed for the in-depth analysis of metabolites in roasted tobacco leaves. Results: The targeted metabolomic analysis identified 991 metabolites in the positive ion pattern and 673 in the negative ion pattern across all treatments. Among these,...