Pathologic assessment and staging of multiple non-small cell lung carcinomas: a paradigm shift with the emerging role of molecular methods. Mod. Pathol. 37, 100453 (2024). Article PubMed Google Scholar Chang, J. C. et al. Comprehensive next-generation sequencing unambiguously distinguishes ...
mutation rate in lung squamous cell carcinoma is only 2.2% [57]. In addition, NF2 fusion inhibiting NF2 function, including NF2-OSBP2 and NF2-MORC2-fusion, have been found in lung cancer [49]. Further research is required to determine the effectiveness of drugs that target the Hippo pathwa...
NSCLC is the most common type of lung cancer, accounting for approximately 85% of the cases. The three most common forms of NSCLC are adenocarcinoma, squamous cell carcinoma as well as large cell carcinoma [7,8,9]. Common cancer treatment approaches include surgery, chemotherapy, and radiation ...
significantly contributing to mortality rates among both male and female populations [1]. Given the considerable diversity in clinical and pathological characteristics, lung cancer can be broadly categorized into two primary types: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)....
The pathophysiology is not clearly understood. It is characterized by a remarkable clinical heterogeneity, and virtually all organs can be affected. Concerning diagnosis, the presence of antinuclear antibodies (ANA) can be found in more than 90% of patients, but the diagnosis is made gathering ...
Lung cancer is the leading cause of cancer-related death worldwide. Non-small cell lung carcinoma (NSCLC) accounts for most of the lung cancer cases and the prognosis of this disease remains poor despite decades of intensive investigation. Thus new insights into underlying mechanisms by which NSCL...
(range, 66–82 years). Primary tumors included adenocarcinoma in 48 cases, alveolar cell carcinoma in 17 cases and large cell carcinoma in seven cases. The study subjects were randomized into the bevacizumab group (intrapleural therapy of bevacizumab combined with cisplatin; n=36), and the ...
Nitric Oxide Regulates Lung Carcinoma Cell Anoikis through Inhibition of Ubiquitin-Proteasomal Degradation of Caveolin-1 Anoikis, a detachment-induced apoptosis, is a principal mechanism of inhibition of tumor cell metastasis. Tumor cells can acquire anoikis resistance which is frequently observed in metast...
renal cell carcinoma31,32,33. However, various studies have demonstrated the downregulation ofTCF21in breast cancer, bladder cancer, and non-small cell lung cancer30. Although this genetic variant has not been evaluated for lung cancer risk in any of the population group in india. This study ...
Despite the importance of radiation therapy as a non-surgical treatment for non-small cell lung cancer (NSCLC), radiation resistance has always been a concern, due to poor patient response and prognosis. Therefore, it is crucial to uncover novel targets