回答和翻译如下:Non-Sink Dissolution.无沉淀溶解。
Non-sink dissolution behavior and solubility limit of commercial tacrolimus amorphous formulations. TRASI NS,PUROHIT HS,WEN H,et al. Journal of Pharmacological Sciences . 2017Trasi NS, Purohit HS, Wen H, Sun DD, Taylor LS. Non-sink dissolution behavior and solubility limit of commercial ...
Due to the rapid dissolution dynamics of carbonate, carbonate-rich soil in non-karst areas can produce carbon sink flux similar to that in karst areas, so the spreading of carbonate powder in non-karst areas could be developed as an enhanced weathering technology which may has a great ...
A model is developed for convenient treatment of data obtained from non-sink dissolution. To demonstrate its utility, the dissolution profiles of calcium sulfate, calcium carbonate and three calcium phosphates were determined by USP dissolution in pH 1. 2 buffer. A model is developed taking into ...
Using sink conditions or too high amount of the sample will increase the dissolution rate and weaken the discrimination between dissolution profiles. Furthermore, the low solubility by choosing a proper pH of the dissolution medium was helpful in getting discriminating dissolution profiles, whereas the...
Solid dispersion technology has been used over the last three decades to improve the dissolution and oral absorption of poorly soluble compounds. While the characterization of dissolution performance of crystalline pharmaceutical systems has long been established, the dynamic nature of the amorphous ...
The objective of this study is to test whether one can consistently generate similar (or superimposable) kinetic solubility profiles (KSP) from a given amorphous solid dispersion (ASD) with different volume, type of dissolution medium, and/or total dose as long as the SI value is kept ...
Petralito S, Zanardi I, Memoli A, Annesini CM, Millucci V, Travagli V. Apparent solubility and dissolution profile at non - sink conditions as quality improvement tools. In: Basnet P, editor. Promising pharmaceuticals. Croatia: InTech; 2012. p. 83-100....
, Apparent Solubility and Dissolution Profile at Non-sink Conditions as Quality Improvement Tools 2012, p. 83.Petralito S, Zanardi I, Memoli A, Annesini MC, Millucci V, Travagli V. Apparent Solubility and Dissolution Profile at Non-Sink Conditions as Quality ...
A general mathematical model was developed to describe a dissolution system for tablets that have undergone attrition and maintained their geometric shape as concentration changed, i.e., starting with sink and ending with nonsink conditions. A computer program, designed for the microcomputer, was ...