Keywords: Human proteome – Redundant peptide sequences – Quantitative proteomic redundancy – Qualitative proteomic redundancyWe describe immune-proteome structures using libraries of protein fragments that define a structural immunological alphabet. We propose and validate such an alphabet as i) composed ...
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Using the methods from Statistical Physics, we analyze the amino acid motifs observed in the non-redundant protein sequence database. In addition to the exhaustive study of the amino acid motif, we also study the correlation function between various amino acids in the primary protein sequences. ...
non-redundant GenBank protein database revealed that a substantial number of spruce transcripts have no obvious similarity to known angiosperm gene sequences... SG Ralph,HJE Chun,N Kolosova,... - 《Bmc Genomics》 被引量: 249发表: 2008年 Conservation of PCDHX in mammals; expression of human...
Redundant protein sequences in biological databases hinder sequence similarity searches and make interpretation of search results difficult. Clustering of ... BE Suzek,H Huang,P Mcgarvey,... - 《Bioinformatics》 被引量: 1217发表: 2007年 Clustering of highly homologous sequences to reduce the size...
(C) Restored CD4+T cell responses by administration of soluble CD100 protein. Wild-type (closed bars) and CD100-deficient mice (open and shaded bars) were immunized with KLH in complete Freund's adjuvant in the hind foot pad. Soluble recombinant CD100 protein (50 μg/mouse) was injected...
Ion pair interactions between protein lysines/arginines and GAG sulfates/carboxylates mediate binding. Neutrophil-activating chemokines (NAC) are GAG-binding proteins, and their sequences reveal high selectivity for lysines over arginines indicating they are functionally not equivalent. NAC binding to ...
COPII vesicle buddingin vivorequires the peripheral membrane protein Sec16p. SEC16 gene was first identified inSaccharomyces cerevisiae7; SEC16 mutations result in a lack of 50 nm vesicles in these mutants8. Sec16p localizes to the ER membrane and has three main functional domains namely the ...
RefSeq is a public database of nucleotide and protein sequences with corresponding feature and bibliographic annotation. The RefSeq database is built and distributed by the NCBI, a division of the National Library of Medicine located at the US National Institutes of Health. NCBI makes RefSeq public...
Recently, BBS proteins and IFT have been shown to function together to cycle ciliary signaling proteins such as G protein-coupled receptors (GPCRs), where BBS proteins mediate the exit of ubiquitinated GPCRs (38). In addition, the entry and exit of BBS proteins is regulated by IFTs, as ...