非编码区(Non-coding region):基因是由成千上万个核苷酸对组成。组成基因的核苷酸序列可以分为不同区段。zhidao.baidu.com|基于44个网页 2. 子为非译码区 ...共有11个表现子(exons)(11),第一个表现子为非译码区(non-coding region)。www.tma.tw|基于5个网页 3. 包发送期间碰撞次数 ... (in
to a non-coding region at FRA7H nearB SchneiderS NagelM KaufmannS WinkelmannJ BodeH G DrexlerR A F MacLeodLeukemia
Specifically, CV2CoV includes 5′ untranslated region (UTR) HSD17B4 and 3′ UTR PSMB3 elements followed by a histone stem–loop motif and a poly(A) sequence (Fig. 1 and Methods). In the present study, we make a head-to-head comparison of the immunogenicity and protective efficacy of ...
A new 5′-non-coding region for human placen- tal insulin-like-growth-factor II mRNA expression. FEBS Lett. 222(1):181-185.Le Bouc Y, Noguiez P, Sondermeijer P, Dreyer D, Girard F, Binoux M, (1987) A new 5′-non-coding region for human placental insulin-like growth factor II...
typically recognizingbinding sitesin the 3′untranslated region(UTR) of mRNA transcripts. There are a myriad of interactions in the interface of miRNAs andepigenetics.Epigenetic mechanismscan silencemiRNAcoding sites, and miRNAs can be the effectors of transcriptional gene silencing, targeting complementary...
prevent proper complex formation, leading to misplicing of premature tRNAs (pre-tRNAs) into their mature form, thereby unbalancing the tRNA repertoire for protein synthesis [248,250]. PHC6 results from a mutation in the intronic region of the mitochondrial pre-tRNA synthetase gene for arginine [...
超保守区(ultra - conservative region, UCRs) 是指在人类、小鼠和大鼠之间显示100%的DNA序列保守性的基因组片段。人类基因组在基因内(39%)、内含子(43%)和外显子(15%)序列中包含481个ucr[194]。这些区域被广泛转录为T-UCR lncrna[195,196]。值得注意的是,t - ucr的表达是由癌症相关应激引起的,如类维生...
miRNA是短ncRNA,约为22～23个核苷酸,其编码基因由RNA多聚酶Ⅱ转录,通过与mRNA 3′端非翻译区(3′ untranslated region, 3′UTR)之间的结合调控mRNA的表达,超过60%的编码基因是miRNA的潜在调控靶点。 2、长链非编码RNA(long non-coding RNA, lncRNA) ...
(Fig.4a; Additional file1: Figure S5b; Additional file2: Tables S12 and S13). CCV rs11642015 falls within a region of open chromatin marked by H3K27ac and H3K4me1, consistent with a putative enhancer element and contactsXLOC-093918in B80T5 normal breast cells and ER-positive and ER-...
Long non-protein-coding RNAs (ncRNAs) are emerging as important regulators of cellular differentiation and are widely expressed in the brain. Here we show that many long ncRNAs exhibit dynamic expression patterns during neuronal and oligodendrocyte (OL)