Assoc,Prof,IvanLambeve,mail,itlambevmail,bg,NONBETA,LACTAMANTIBIOTICS,MedicalUniversityofSofia,FacultyofMedicineDepartme
The invention provides a newly discovered oxadiazole class of antibiotics. The oxadiazoles impair cell-wall biosynthesis and exhibit activities against the Gram-positive bacteria such as the bacterium Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA) and vancomycin-resistant and ...
Binding of a non-beta-lactam- antibiotic to penicillin-binding proteins. Nature (London) 325:179-180.Nozaki Y , Katayama N , Ono H , Tsubotani S , Harada S , Okazaki H , et al. Binding of a non-beta-lactam antibiotic to penicillin-bind- ing proteins. J Antimicrob Chemother. 1991;...
especially beta-lactams, and non-steroidal anti-inflammatory drugs. Most publications on allergy to antibiotics have focused on hypersensitivity to penicillins and cephalosporins, while studies on reactions to each specific non beta-lactam are scarce or involve only case reports or a small ...
Ceftazidime/avibactam: a novel cephalosporin/nonbeta-lactam beta-lactamase inhibitor for the treatment of complicated urinary tract infections and complicated ... V Celeste,H Jose,A Nishaal - 《Drug Design Development & Therapy》 被引量: 9发表: 2016年 Ceftazidime–avibactam: novel antimicrobial combi...
The diagnosis of non-immediate type beta-lactam allergy was determined by provocation tests (n=11) prick/epidermal tests (n=3), patch tests (n=2). Only angioedema was found to increase the risk for diagnosis of non-immediate type beta-lactam allergy (OR:3.8, 95%CI:1.2-11.4, p=0.009)...
Primary goal of the study was to check various combinations of beta-lactam antibiotics with daptomycin (DAP) and assess the potential of synergy and conclude which could be the superior combination. Study also evaluated potential of beta-lactam antibiotics to enhance activity of LL-37, which is ...
In a study of Caubet et al., both skin tests and oral challenge test (OCT) were performed in 88 children with a history of mild non﹊mmediate reactions with a betalactam antibiotic: 11 had an immediate positive intradermal test, but only 4 of them had a mild exanthema when challenged (...
On June 23, 2022, the U.S. Food and Drug Administration (FDA) notified the pharmaceutical industry of an important update to Non-Penicillin Beta-Lactam Drugs: A CGMP Framework for Preventing Cross-Contamination, published on April 17, 2013.1This new draft guidance broadens ...
Background: Extending the drug provocation test(DPT) period is recommended for patients with suspected nonimmediate beta-lactam antibiotic(BLA) allergy and negative DPT. There is no consensus regarding the duration of prolonged provocation. Objective: We aimed to determine the negative predictive value...