Long noncoding RNALncRNAlincRNAMicroarrayGene expression profilingArraystar LncRNA microarrays are designed for global gene expression profiling of both LncRNAs and mRNAs on the same array. The array contents feature comprehensive collections of LncRNAs and include entire sets of known coding mRNAs. Each...
Non-coding RNA Research(《非编码RNA研究》(英文),简称NCRNA)创刊于2016年12月,是由中国科学院主管,科学出版社主办,科爱公司运营的高质量国际开放获取期刊,旨在发表高水平的研究论文和综述,传播前沿研究,展示非编码RNA在现代医学和研究中不断演变的重要性。 NCRNA作为一本专注于非编码RNA的英文学术期刊,旨在为国内...
常见非编码RNA介绍 非编码RNA(non-coding RNA,ncRNA),指的是不被翻译成蛋白质的一类RNA,转录ncRNA的DNA序列叫非编码RNA基因。随着生物学的发展和多学科的相互渗透,人们对ncRNA的认识日渐加深,近十几年来… 大名不知道发表于小小芦聊科... 编码RNA与非编码RNA(一) lcy19...发表于生化杂谈打开...
Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles for 1707 human lncRNAs in the NCI60 cancer cell line panel using a high-throughput nanowell R...
非编码RNA (non-coding RNA,ncRNA)指不翻译成多肽的RNA。按照长度不同,短于200nt的归为小非编码RNA (small non-coding RNAs,sncRNAs),长于200nt的归为长非编码RNA (long non-coding RNAs,lncRNAs)。 非编码RNA参与的复杂多变的调控过程对于血脂代谢和动脉粥样硬化的发生发展更为重要。
In recent years, research into long non-coding RNA (lncRNA) has emerged as a captivating frontier in molecular biology, revealing intricately woven regulatory networks that govern gene expression. BOC Sciences is at the forefront of lncRNA research, offering comprehensive analysis services. We ...
6月18日,Nature Review Drug Discovery发表了一篇题为“Noncoding RNA therapeutics — challenges and potential solutions”的文章,对非编码RNA(ncRNA)疗法可能面临的挑战和解决方案进行了总结。 过去的十年里,基于RNA的疗法在临床应用方面发挥了巨大作用,主要采用(ASO)反义寡核苷酸和小干扰核糖核酸(siRNA)这两种技术。
Although most of the non-coding RNA (ncRNA) species were initially dismissed as products of spurious transcription, a wide spectrum of ncRNA regulatory mechanisms is now emerging. ncRNA expression in the brain is dynamically regulated in an activity-dependent and spatiotemporally controlled manner, sug...
A long noncoding RNA protects the heart from pathological hypertrophy. Nature 514, 102–6 (2014). CAS PubMed PubMed Central ADS Google Scholar Johnson, A. D. et al. Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study. ...
ncRNA为蛋白质编码的RNA分子,而是在细胞内执行其他功能。ncRNA基因有许多类型,其中一些包括: 转移RNA(tRNA):tRNA负责在蛋白质合成过程中将氨基酸带到核糖体上。有20种不同的tRNA基因,每种基因都编码一种特定的氨基酸。 核糖体RNA(rRNA):rRNA是核糖体的主要组成部分,是负责合成蛋白质的细胞机器。有几种不同类型的rR...