The invention provides a newly discovered oxadiazole class of antibiotics. The oxadiazoles impair cell-wall biosynthesis and exhibit activities against the Gram-positive bacteria such as the bacterium Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA) and vancomycin-resistant and ...
非beta-内酰胺类抗生素(英文PPT)Nonbeta-lactam antibiotics MedicalUniversityofSofia,FacultyofMedicineDepartmentofPharmacologyandToxicology NONBETALACTAM ANTIBIOTICS Assoc.Prof.IvanLambeve-mail:itlambev@mail.bg Streptomycin Streptomycinisanaminoglycoside antibiotic.Itsantibacterialactivityisduetoitbindingtothe30Ssubunitof...
Anke T, Oberwinkler F, Steglich W, Schramm G (1977) The strobilurins - new antifungal antibiotics from the basidiomycete Strobilurus tenacellus (Pers. ex Fr.) Sing. J Antibiot 30:806–810 CrossRef Anke T, Hecht HJ, Schramm G, Steglich W (1979) Antibiotics from basidiomycetes. IX. Oude...
β-内酰胺类抗菌药物是常见的导致全身过敏的药物,喹诺酮类、糖肽类、大环内酯类、四环素类、林可霉素、氨基糖苷类等非β-内酰胺类的抗菌药物通常是安全的抗菌药物,但它们也可以发生速发型和迟发型超敏反应。该文通过对非β-内酰胺类抗菌药物超敏反应综述,加强临床对此类抗菌药物超敏反应的认识,提高医护人员对非...
Beta-lactam antibiotics (BLA) are used to treat CAM. It is uncertain if women who cannot receive BLA attain similar benefit from treatment of CAM with non-BLA. 关键词: antibiotics cesarean chorioamnionitis intraamniotic infection penicillin wound infection 年份: 2020 ...
Interaction of Beta-Lactam Antibiotics with the Penicillin-Binding Proteins of Penicillin-Resistant Streptococcus pneumoniae Anti-Bredt bridged bicyclo[3.2.1] γ-lactams were designed as inhibitors of penicillin binding proteins (PBPs). The compounds were prepared by a carbenoid ... Ikeda,F.,Yokota,...
Mtb β-lactamase (BlaC) is extremely efficient in hydrolyzing ß-lactam antibiotics which renders/leads to protection and/or resistance to this bug. There is a compelling need to develop new non-lactam inhibitors which can bind and inhibit BlaC, but cannot be hydrolyzed, thus neutralizing this...
Various mechanisms for the alkaline hydrolysis of aza-β-lactam (na), oxo-β-lactam (oa) and thio-β-lactam compounds (sa) were analysed on the basis of PM3 calculations in order to identify potential differences with classical β-lactam antibiotics. Changes in the tetrahedral intermediate were...
Diagnosis of immediate allergic reactions to beta‐lactam antibiotics Initially, skin tests to PPL were considered to be positive in more than 70% of patients with IgE mediated clinical reactions to penicillin, and most studi... MJ Torres,M Blanca,J Fernandez,... - 《Allergy》 被引量: 1086...
(14.9%).Adverse cutaneous drug reactions in our study population were mainly induced by beta-lactam antibiotics and non-steroidal anti-inflammatory drugs. Th... Mahmood,Farshchian,Akram,... - 《Clinical Cosmetic & Investigational Dermatology》 被引量: 2发表: 2015年 Variants of Fixed Drug Eruptions...