实验原理 NAFLD是指除外酒精和其他明确的损肝因素所致的肝细胞内脂肪过度沉积为主要特征的临床病理综合征,与胰岛素抵抗和遗传易感性密切相关的获得性代谢应激性肝损伤。包括单纯性脂肪肝(SFL)、非酒精性脂肪性肝炎(NASH)及其相关肝硬化。非酒精性脂肪性肝病除可直接导致失代偿期肝硬化、肝细胞癌和移植肝复发外,还可影...
livernonalcoholic steatohepatitisPNPLA3simple sugarstriglyceridesSummary The metabolic syndrome (MetS) represents a cluster of metabolic abnormalities that identify people at risk for diabetes and cardiovascular disease (CVD), while nonalcoholic fatty liver disease (NAFLD) is defined as a condition with ...
非酒精性脂肪肝(Nonalcoholic Fatty Liver Disease,NAFLD)是指酒精和其它明确的损肝因素之外所致的肝细胞内脂肪过度沉积引发的代谢应激性肝脏损伤。非酒精性脂肪性肝炎(Nonalcoholic Steatohepatitis,NASH)是NAFLD进展而来的严重慢性肝脏疾病,流行病学数据显示,15%～25%的NAFLD患者最终会发展为NASH。 全球平均每3个人中就...
NASH(non-alcoholic steatohepatitis),即非酒精性脂肪性肝炎,是由肝脏中脂肪堆积引起的肝脏疾病和炎症。根据流行病学数据,全球酒精性脂肪肝病(non-alcoholic fatty liver disease,NAFLD)发病率约25%,这些患者约有10-20%的可能进展为NASH,全球各地NASH发病率约为1.5%至6.5%,中国约为3.5%(即目前美国NASH患者人数约为1...
非酒精性脂肪性肝病（nonalcoholic fatty liver desease NAFLD） 是一种肝组织病理学改变与酒精性肝病相类似但无过量饮酒史的临床综合征。NAFLD疾病谱包括单纯性脂肪肝、非酒精性脂肪性肝炎（nonalcoholic steatohepatitis NASH）和脂肪性肝硬化三种主要类型。流行病学 NAFLD常合并肥胖和或2型糖尿病、高脂血症。NAFLD...
Non-alcoholic fatty liver disease (NAFLD) is associated with low level of physical activity: a population-based study BACKGROUND: High intensity exercise improves metabolic status and may potentially mobilise hepatic fat. AIM: To assess the level of physical activity (PA) ... L Gerber,M Otgon...
Fatty Liver Disease Types There are two main types of FLD: 1. Metabolic dysfunction-associated steatotic liver disease (MASLD) This type used to be called nonalcoholic fatty liver disease (NAFLD). It is very common in the U.S., affecting 1 in 3 adults. Researchers aren't exactly sure wh...
There is currently no licensed treatment for NAFLD, and most people are managed by their general practitioner with a focus on lifestyle advice such as weight loss.Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease from fatty liver to non-alcoholic steatohepatitis, fibrosis, and ...
非酒精性脂肪性肝病(Nonalcoholic Fatty Liver Disease,NAFLD)是一种与胰岛素抵抗和遗传易感密切相关的代谢应激性肝脏损伤,疾 病谱包括非酒精性肝脂肪变(NAFL)、非酒精性脂肪性肝炎(NASH)及NASH相关肝硬化和肝细胞癌。 NASH表现为5%以上的肝细胞脂 肪变合并小叶内炎症和肝细胞气球样变性,大约有15%~25%的NAFLD会...
S Barkin.Current biochemical studies of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) suggest a new therapeutic approach... P Hookman,JS Barkin - 《American Journal of Gastroenterology》 被引量: 105发表: 2003年 Current biochemical studies of Non-Alcoholic Fatty...