Comparison of Alcohol vs Non-Alcohol-Related Cirrhosis: Trends in Hospitalization, Inpatient Mortality, and Cirrhosis-Related Complications in United States from 2002 to 2011: 757Devani, KalpitCharilaou, ParisJohn, FebinPatel, PranavYoung, Mark
The patho- logical picture resembles that of alcohol-induced liver injury, but it occurs in patients who do not abuse ... P Angulo 被引量: 1039发表: 2002年 Non-alcoholic fatty liver disease (NAFLD) and the metabolic syndrome (MS) - ScienceDirect The prevalence of nonalcoholic fatty liver ...
We aim to (1) determine the immuno-pathology of alcohol-induced liver damage, (2) examine the role of genetics in the development of ASH, (3) propose diagnostic markers of ASH and NASH, (4) examine age differences, (5) develop common research tools to study alcohol-induced effects in ...
2019), nonalcoholic fatty liver disease (NAFLD) covers a diseases spectrum, initiating with hepatic steatosis which is defined by the presence of ≥5% hepatic fat (referred to steatosis) in the absence of any secondary cause of hepatic steatosis such as chronic viral hepatitis and alcohol ...
(nonalcoholic steatohepatitis, NASH) and ultimately progressing to fibrosis/cirrhosis and potentiallyhepatocellular carcinomain theabsenceof excessive alcohol consumption(Anstee et al., 2013; Anstee et al., 2011). NAFLD is strongly associated with themetabolic syndrome(MetS) including obesity,type...
Nonalcoholic steatohepatitis (NASH) is an hepatic disorder with histologic features of alcohol-induced liver disease that occurs in individuals who do not consume significant alcohol. NASH is believed to be one of the most common explanations for abnormal liver chemistries in American adults. Risk fac...
alcohol misuse, obesity, inactivity and diabetes. Prognostic markers could help patients with ALD through better disease management to avoid decompensated cirrhosis. Furthermore, the molecular pathophysiology of ALD is incompletely understood and there are currently no liver-specific interventions against the...
(alcohol dehydrogenase 1b) and p.Cys282Tyr inHFE(homeostatic iron regulator). These two variants are associated with cirrhosis through alcohol consumption (ADH1B)37and hemochromatosis (HFE)38, rather than solely through hepatic fat. Similarly, the effects of the 18 variants on HCC were ...
Nonalcoholic fatty liver is the most common disorder that refers to a higher accumulation of fat in the hepatic cells due to obesity and diabetes in people who do not abuse alcohol [39] (Fig. 8.1). Although the presence of fat in the liver is abnormal, it does not harm the liver. The...
Patients were excluded if they had cirrhosis; other causes of chronic liver disease; a current or recent (within 5 years) history of significant alcohol consumption (>210 g or >140 g per week in men or women, respectively); a bilirubin level >ULN; or glycosylated haemoglobin ≥9.5% or...