Boiko, T. et al. Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon.Neuron30, 91–104 (2001).References 21 and 22 were the first to show a developmental switch in Na+channel isoforms at the nodes of Ranvier. ArticleCASPubMedGoogle Scholar Gold...
Deals with the challenges faced by cell biologists in the assembly of neuronal specializations. Terms used in reference to postsynaptic density; Contents of the nodes of Ranvier, which are gaps in the myelin sheath that allow the efficient propagation of action potentials; Situation when the ...
Development of nodes of Ranvier The architecture and function of the nodes of Ranvier depend on several specialized cell contacts between the axon and myelinating glial cells. These sites... JA Girault,E Peles - 《Current Opinion in Neurobiology》 被引量: 213发表: 2002年 Myelination of Congenita...
Sprouting of mammalian motorneurones at nodes of ranvier: the role of the denervated motor endplate Keynes RJ, Hopkins WG, Brown MC (1983) Sprouting of mammalian motor neurones at nodes of Ranvier: the role of the denervated motor endplate. Brain ... Roger J. Keynes and William G. ...
The architecture and function of the nodes of Ranvier depend on several specialized cell contacts between the axon and myelinating glial cells. These sites contain highly organized multimolecular complexes of ion channels and cell adhesion molecules, closely connected with the cytoskeleton. Recent findings...
Rapid action potential propagation along myelinated axons requires voltage-gated Na+ (Nav) channel clustering at nodes of Ranvier. At paranodes flanking nodes, myelinating glial cells interact with axons to form junctions. The regions next to the paranodes called juxtaparanodes are characterized by...
Transmembrane scaffolding proteins in the formation and stability of nodes of Ranvier The function of myelinated fibers depends on the clustering of sodium channels at nodes of Ranvier, the integrity of the myelin sheath, and the existence o... JA Girault,K Oguievetskaia,M Carnaud,... - ...
The intermittent staining along axons suggested that Caspr2 could be expressed in the juxtaparanodal region, close to the nodes of Ranvier. To investigate this possibility, we double labeled sections of rat optic nerve with antibodies for Caspr2 and Caspr. As shown in Figure 5, Caspr2 expressio...
The axon is a part of the neuron that is responsible for sending messages away from the nerve body. Axons are sometimes also called nerve fibers. The structure of the myelin sheath comes mostly from lipids, with some proteins mixed in as well....
Microglia-neuron communication at nodes of Ranvier depends on neuronal activity through potassium release and contributes to myelin repairdoi:10.1101/2020.09.02.279562R. RonzanoT. RouxM. ThetiotM.S. AigrotL. RichardF.X. LejeuneE. MazuirJ.M. Vallat...