Function The role of myelin in both the CNS and the PNS is to insulate the nerve fiber and, as a result, to accelerate the conduction of the action potential. In this process, nodes of Ranvier are important for the amplification of the action potential. More specifically node’s voltage-...
The integrity of myelin and the glial‐associated paranodal structures at the node of Ranvier is critical for normal AN activity and axonal survival and function in the central auditory nervous system. However, little is known about the node of Ranvier''s spatiotemporal development in the AN, ...
Roots BI (1984) Evolutional aspects of the structure and function of the nodes of Ranvier. In: Zagoren JC, Fedoro S (eds) The node of Ranvier. Academic Press, Orlando, pp 1±29Roots BI (1984) Evolutional aspects of the structure and function of the nodes of Ranvier, in The Node...
Glial cells of the auditory nerve regulate the formation of the nodes of Ranvier that are needed for regeneration of action potentials and proper hearing function. Here we identify and describe the distinct features of two novel types of Ranvier nodes-the axonal node and the ganglion node-in ...
Node of RanvierSaltatory conductionVoltage-gated K+ channelPrevious immunohistochemical studies have shown the expression of KCNQ2 channels at nodes of Ranvier (NRs) of myelinated nerves. However, functions of these channels at NRs remain elusive. In the present study, we addressed this issue by ...
Two distinct types of nodes of Ranvier support auditory nerve function in the mouse cochleadoi:10.1101/2021.02.07.430087Panganiban ChBarth JlTan JNoble KvMcClaskey CmDias JwHarris KcLang HCold Spring Harbor Laboratory