NOD样受体（Nod-like receptor, NLR）家族是机体最大的一类模式识别受体；目前认为NLR感知识别相应模式分子后，可通过自身寡聚化组装形成大型信号分子机器, 如NLRP3，NLRC4等形成的炎症小体（Inflammasome），NOD2等形成的Nodosome，从而激活NF-κB通路、MAPK通路、细胞焦亡等，释放TNFα，IL-1β和IL-18等炎性细胞...
近日,福建医科大学郑春福教授在International Journal of Biological Macromolecules(IJBM)在线发表了题为:The emerging roles of NOD-like receptors in antiviral innate immune signaling pathways的综述论文。 NOD样受体(NOD-like receptors, NLRs)是宿主的一类模式识别受体,可识别病毒的病原相关分子模式。众所周知,NLRs调...
NOD-like receptor (NLR)inflammasomedevelopmentgut homeostasismajor histocompatibility complex (MHC)NODosomeinnate immunityNFκBIL-1βdoi:10.1002/9780470015902.a0026236Christine ArnoldUniversity of Hohenheim Stuttgart GermanyIoannis KienesUniversity of Hohenheim Stuttgart GermanyAnna S Sowa...
MCE 站:NOD-like Receptor 品牌:MedChemExpress (MCE) 概述:核苷酸寡聚结构域 (NOD) 样受体 (NLR) 是关键的细胞质模式识别受体 (PRR),在宿主先天免疫反应和免疫稳态中发挥重要作用。人类中有 23 个 NLR 家族成员,小鼠中有至少 34 个 NLR 基因。 NLR 在许多细胞类型中表达,包括免疫细胞和上皮细胞,尽管某些...
NODNOD-like Receptor (NLR) ¥ 373 现货 规格 数量 Troxerutin 维脑路通, 曲克芦丁, Trihydroxyethylrutin T07727085-55-4 Troxerutin (Trihydroxyethylrutin) 是一种天然生物类黄酮芦丁的三羟乙基化衍生物,也被称为维生素 P4,可抑制活性氧的产生并抑制 ER 应激介导的NOD 活化。
NODNOD-like Receptor (NLR) ¥ 373 现货 规格 数量 Troxerutin 维脑路通, 曲克芦丁, Trihydroxyethylrutin T07727085-55-4 Troxerutin (Trihydroxyethylrutin) 是一种天然生物类黄酮芦丁的三羟乙基化衍生物,也被称为维生素 P4,可抑制活性氧的产生并抑制 ER 应激介导的NOD 活化。
Toll like receptor (TLR) belong to animal pattern recognition receptor family. Toll样受体(TLR)蛋白家族属于动物模式识别受体家族。 2. By far,ten toll like receptors were found in human and mammalian. Toll样受体是一类在进化中高度保守的Ⅰ型跨膜蛋白,识别病原体相关分子模式,为先天性免疫的重要成分...
例句与“ NOD-like receptor " 变形 干 匹配词 所有 精确 任何 These proteins contain domains similar to the NOD Like Receptors and Toll-like receptors utilized in animal innate immunity. WikiMatrix Certain intracellular receptors of the immune system are cytoplasmic receptors; recently identified ...
This study shows that the plant TIR-type NLRs RPS4 and RRS1 function together as a receptor complex in which the two NLRs have distinct roles in pathogen recognition and immune signalling. CAS PubMed Google Scholar Bernoux, M. et al. Structural and functional analysis of a plant ...
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activa... H Wen,E Miao,JY Ting - 《Immunity》 被引量: 333发表: 2013年 The Nod-Like Receptor Family Member Naip5/Birc1e Restricts Legionella...