促进细胞的凋亡,并且在体外实验中用SK-BR-3乳腺癌细胞系和对雌激素敏感的MCF-7乳腺癌细胞系构建了NOD1敲除和NOD1过表达的细胞,发现NOD1在这2个细胞系中均能调控细胞凋亡通路,随后他们通过scid小鼠移植瘤模型证实NOD1对雌激素敏感的肿瘤...
NOD 样受体通路在急性腹腔感染早 期对大鼠肠屏障的作用机制初探 [J]. 中华危重病急救医学, 2013, 25 (9): 527蛳532. DOI:10.3760/cma.j.issn.2095蛳4352.2013. 09.005. Xiao YT, Li GX, Wang XM. Effect mechanism of NOD like receptor signaling pathway on intestinal mucosal barrier of rat during ...
细胞焦亡过程涉及多种炎症小体信号通路的激活,其中对NOD样受体家族Pyrin域蛋白(NOD-like receptors family Pyrin domain containing,NLRP)3炎症小体的研究较深入。目前,研究结果证实,NLRP3炎症小体诱导的细胞焦亡在骨髓增生异常综合征(myelodysplastic syndromes,MDS)发病中发挥重要作用[ 1 ]。但是细胞焦亡是否参与除MDS...
它们的功能已被广泛研究[4-6]，揭示了它们在宿主防御病原体起到关键作用，如单核细胞增多性李斯特菌，幽门螺杆菌，葡萄球菌等。在人体中，NOD 受体，特别是NOD2受体的变异所致的NOD 信号通路失调与炎症性肠病——克罗恩病有关。NOD 通路的异常活化还会导致Blau 综合征或早发的肉瘤样病变，两者都是以家族性肉芽...
signaling pathways process.:To study the expression of cellular pattern recognition receptors nucleotide-binding oligomerization domain containing in the corneal cell and the role of activate the innate immune of corneal cell, to explore the mutual relations with the Toll-like receptor TLR4 in this ...
Mitchell HM: The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-control Study and Gene Expression ... N Castaño-Rodríguez,NO Kaakoush,AL Pardo,... - 《Human Immunology》 被引量: 51发表: 2014年 The NOD-like receptor signalling pathw...
Get Print Copy of this Pathway View NOD-like Receptor Signaling Pathways Image Related Information NLRP10 Is Required for Dendritic Cell-mediated Initiation of the Adaptive Immune Response NOD-like Receptors and the Inflammasome Obesity-Induced Activation of the Nlrp3 Inflammasome Promotes Insulin Resistan...
An overview of the NOD-like receptor signaling pathway, introduction, the regulation of pathway and clinical significance.
Effect of Guizhi Tang drug serum on the expression of Toll-like receptors and downstream signaling components in RAW 264.7 cells; 桂枝汤含药血清对小鼠巨噬细胞Toll样受体3、4型及其下游信号转导通路元件的影响 更多例句>> 4) toll like receptor Toll样受体 1. Toll like receptor (TLR) belong to...