利用核磁共振(NMR)研究固体材料的技术正在迅速发展,它提供了有关无机和生物分子的结构、运动学和动力学特性的独特见解。材料科学家使用固体NMR检查晶体、非晶体、复合材料,以及悬浮液和混合试样的液体或气体成分。 应用范围包括燃料电池表面电化学研究、晶体粉末结构测定,以及原油馏分的分子结构研究。在结构生物学方面,固体...
nuclear magnetic resonance (NMR) spectroscopy is being increasingly used for the detection of illicit drugs. NMR has the advantages that it requires no compound specific reference standards
Fragranced notes Cassis base 345B, undecavertol, 1,3-oxathiane oxane, isospirene Perfume can be so romantic But the chemical components underpinning the often-enticing and seductive smells of fragrances are, one might say equal parts art and science. One of the most intriguing elements o...
It should be noted that the latter is quite temperature(1) For recommendations on the publication of NMR data, see: IUPAC Commission on Molecular Structure and Spectroscopy. Pure Appl. Chem. 1972, 29, 627; 1976, 45, 217. dependent (vide infra). Also, any potential hydrogenbond acceptor ...
A strategy, based on solid-state NMR spectroscopy, for determining the structure of an oligomeric, seven-helix membrane protein (Anabaena sensory rhodopsin) in a lipid environment is described. Determination of structure of integral membrane proteins, es
Magnetic resonance spectroscopy allows identifying metabolite content of the tissue and estimating the metabolite concentration. Map of metabolite concentration along with the MR image allows proper classification of many pathologies, for example progressive tumorous tissue identification in brain. Standard ...
Trimethylamine-N-oxide: its hydration structure, surface activity, and biological function, viewed by vibrational spectroscopy and molecular dynamics simulations. Phys. Chem. Chem. Phys. 19, 6909–6920 (2017). Article CAS PubMed Google Scholar Pais, T. M., Lamosa, P., Garcia-Moreno, B., ...
The specific interaction of pseudohevein with N,N′,N′′-triacetylchitotriose has been analyzed by 1H-NMR spectroscopy. Because of its small size, with a chain length of 45 amino acids, this lectin is a prime target to solution-structure determination by NOESY NMR experiments in water. The...
2003年第一个完整的人类基因组的发布标志着生物学研究的一个里程碑,在各种替代能源和个性化医学等领域具有巨大的潜力。认为微小缠结氨基酸或核酸是控制甚至完全消除癌症、使人衰弱的神经肌肉疾病或HIV等毁灭性疾病的关键,确实十分惊人。 事实上,人类基因组计划的成功仅仅是第一步。要想做到让每个人都得到定制疫苗或基因...
近年来,在精神活性物质的消遣性使用急剧增加之后,全球范围内的吸毒现象已达到流行水平。据估计,全球每100人中就有1人在使用可卡因、安非他命和摇头丸等兴奋剂。尽管这些药物是非法的,但它们在世界各地被广泛贩运,可能会导致不可预测的暴力行为和严重的长期健康问题。