Additionally, the website will regularly introduce new spectral problems, ensuring a continuous learning resource for students. Another web-based platform that helped students practice proton NMR questions is nmr.cheminfo.org, introduced by Patiny et al. (2018). This online platform offers students ...
I realize there are a lot pro's on this board as well as of other students who, like me, are still struggling with NMR problems. I was wondering if any of the pro's (or students who are really good at NMR) could give me some tips on how they learned to do well with NMR/spectr...
In practice, we tested both glass fiber and paper plugs that provided similar performance. Yet, because the plug itself and the gas collected below it make the cell conductivity spatially inhomogeneous, using the porous plug required us to modify the operational principle previously used in eNMR ...
NMR spectroscopyIn recent years, a revolution in the practice of organic chemistry has been brought about by the application of physical methods. Nuclear magnetic resonance spectroscopy has been especially important in this regard, but so many papers have been published dealing with its uses in ...
Protein solubility and stability depend on the co-solutes present. There is little theoretical basis for selection of suitable co-solutes. Some guidance is provided by the Hofmeister series, an empirical ordering of anions according to their effect on so
The use of spatially-localised spectroscopy is standard practice for the analysis of heterogenous samples in the field of MRI/MRS. Examples also exist of the use of a high-resolution NMR system to characterise, with 1D-localised spectra, samples that are “naturally” spatially heterogenous (i.e...
Melanoma presents a major challenge in medical practice, due to difficulty in diagnosis, poor response to avail- able therapies and high incidence in western populations1. The study of melanoma has greatly benefited from the use of cell lines, which allow the investigation of progressive changes ...
the absence of the signals of any upstream raw material analytes in the UFDF pool implies that they were adequately cleared throughout the purification process. Indeed, it is currently common practice in the industry to test for upstrea...
From inspection of the examples shown in Fig.3a, it can be seen that the experimental model is usually one of the best structures, as one would expect. Also apparent is that as GDT increases (i.e., as decoys become more like the experimental structure), both the validation scores tend ...
Summary of NMR spectrum pre-processing and quantitative practice The use of sophisticated curve-fitting software and specifically created databases of NMR spectra of pure metabolites obtained at appropriate pH levels and spectrometer frequencies is required for spectrum analysis (100–900 MHz) (Fig.4)....