View PDFView articleView in ScopusGoogle Scholar An overview of consensus conclusions by the wwPDB NMR Validation Task Force providing recommendations for validation of protein NMR structures in three phases: (i) validation methods ready to implement immediately as part of a consensus NMR structure va...
(out of 62 protein-ssRNA complexes, 33 were solved by NMR and 29 by X-ray crystallography). This emphasises that NMR is a major technique for the investigation of such complexes. This fact can be explained by numerous intrinsic properties of protein-ssRNA complexes[9],[10],[11]. First, ...
Hence, solving the problems relevant to chemistry and condensed-matter physics is expected to be the first successful application of quantum computers. In this Article, we propose another class of problems from the quantum realm that can be solved efficiently on quantum computers: model inference ...
Assignment problems of 'push-pull' triacetylenes 3 have been solved by 13C labelling of the CO group of 3a.doi:10.1002/hlca.19910740713Neuenschwander, MarkusBartlome, AndreasWILEY‐VCH Verlag GmbHHelvetica Chimica Acta
(PDBID:2PHY,replacing1PHY),whichwasdeterminedbyx-raycrystallography.PhosphoactiveYellowProteinwasincorrectlysolvedduetoproblemsinelectrondensityinterpretation,andsubsequentlyamajorchangeinthefoldwasdetermined[2].Currently,x-raycrystallographyandnuclearmagneticresonance(NMR)spectroscopyaretwomaintechniquesforbiomolecular...
While it is probable that some of these will be successfully sidestepped during the next few years, it is unlikely that they will all be solved; thus current liquid state NMR techniques are unlikely to provide a viable technology for practical quantum computation. Get PDF (135K) More content...
(MAS)ofasample,which,byeliminatingchemicalshiftanisotropyinpowdersamples,solvestwoproblems:allowssiteassignmentsandincreasessignal-to-noise(S/N)ratiobycreatingnarrowspectralpeaks.MASalsoaveragesthedipole-dipolecouplings,andtheyshouldbereintroducedbyusingarotationalresonance.10Rotor-synchronizedrecouplingsequences11...
10. The method in accordance with claim 6, wherein in the forming the spin-lattice relaxation time, the saturation pulse sequence is omitted and the estimate for the spin-lattice relaxation time T1 is numerically solved from the equation: ∑A1∑A2=1+(n-1)*(1-exp(-t...
the interpretation or rationalization of many ob- served phenomena cannot be reduced to an equation or series of equations. Such problems are typically solved using intuition and experience and draw upon a great deal of empirical knowledge about the problem area. It is not sur- prising therefore,...
(9) is solved based on the fact that a satisfying Haa=−ha (9) is a prerequisite for a satisfying Eq. (5). Note that Ha and ha are respectively given by H a = [ h p - 1 h p - 2 ⋯ h 0 h p h p - 1 ⋯ h 1 ⋮ ⋮ ⋱ ⋮ h N - 2 h N - 3...