The disclosed invention is based on the observation that functional NMDA receptors are present on osteoclasts. Use of NMDA antagonists to inhibit bone resorption is disclosed, useful therefore in the treatment of bone disorders such as osteoporosis and Paget's disease. The NMDA antagonists used were...
Use of nmda receptor antagonists for treatment of urologic tumorsA method for treating a subject for urologic cancer or a urologic cancer related disorder comprises administering an NMDA receptor antagonist such as memantine to the subject.doi:WO2009016486 A2TIRAN, Zohar...
NMDA receptor antagonist 4名称 英文名 NMDA receptor antagonist 4 NMDA receptor antagonist 4生物活性描述 NMDA受体拮抗剂4(IIc)是一种无竞争性、电压依赖性、口服活性NMDAR阻滞剂,IC50为1.93µM。NMDA受体拮抗剂4显示出预测的血脑屏障(BBB)通透性为阳性,可用于阿尔茨海默病的研究【1】。
The invention relates to the use of pharmaceutical compounds having NMDA antagonist activity for treating certain conditions in the gastrointestinal tract, such as functional gastrointestinal disorders, and in particular irritable bowel syndrome (IBS). The invention also relates to pharmaceutical compositions...
中文名称: 化合物 NMDA receptor antagonist 5 英文名称: NMDA receptor antagonist 5 CAS号: 2415998-36-4 品牌: TargetMol 产地: 美国 保存条件: Shipping with blue ice. 产品类别: 抑制剂 货号: T61470 Product Introduction Bioactivity 名称 NMDA receptor antagonist 5 描述 NMDA receptor antagonist...
A series of variants of the neuroactive 17-residue γ-carboxyglutamate-(Gla)-containing polypeptide, conantokin-G (con-G), were synthesized with the intention of determining those features that were important for its N-methyl-d-aspartate (NMDA) receptor-targeted antagonist activity and for adoption...
Use of the Glutamate NMDA Receptor Antagonist PK-Merz in Acute Stroke .Neuroscience and Behavioral Physiology 2010;40(5):529-32.Krivonos, O.V.; Amosova, N.A.; Smolentseva, I.G. Use of the glutamate NMDA receptor antagonist PK-Merz in acute stroke. Neurosci. Behav. Physiol. 2010, 40...
英文别名: NMDA receptor antagonist 5;5H-Indeno[1,2-d]pyrrolo[2,1-b]oxazol-1(2H)-one, 3a-(4-bromophenyl)-3,3a,4a,9b-tetrahydro-, (3aR,4aS,9bR)-中文名:化合物 NMDA RECEPTOR ANTAGONIST 5中文别名: 化合物 NMDA RECEPTOR ANTAGONIST 5 CBNumber: CB412758689 ...
MCE 国际站:NMDA receptor antagonist-3 产品活性:NMDA receptor antagonist-3 是一种 NMDA 受体拮抗剂,在 SH-SY5Y 和人脂肪间充质干细胞中具有显著的恢复率(40.0 %,100 μM)和安全毒理学特征。 研究领域:Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点:iGluR 相关产品:D-AP5 | Dizocilpine...
中文名称:化合物 NMDA receptor antagonist 5英文名称:NMDA receptor antagonist 5 CAS:2415998-36-4品牌:TargetMol 产地:美国保存条件:Shipping with blue ice. 产品类别:抑制剂 货号:T61470 Product Introduction Bioactivity 名称NMDA receptor antagonist 5