1) NMDA receptor agonist NMDA受体激动剂例句>> 2) NMDA receptor antagonist NMDA受体拮抗剂 1. objective The effect was investigated to induce NSC proliferation and differentiation in the adult rat SGZ、SVZ and cortex by NMDA receptor antagonist administration following focal ischemic insults produced ...
This invention relates to stable pharmaceutical compositions of the NMDA receptor agonist, (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol], methods of preparing such pharmaceutical compositions and methods of treating stroke, spinal cord trauma, traumatic brain ...
中文名：D-丝氨酸;D-蚕丝氨基酸;促皮质25肽;锶胺酸;D-2-氨基-3-羟基丙酸D-β-羟基丙氨酸;内源性NMDA受体共激动剂 英文名：D-Serine；endogenous NMDA receptor co-agonist;β-Hydroxyalanine;(R)-Serine;S-serine;NSC 77689;NSC-77689;NSC77689 CAS号：312-84-5 结构式：C([C@H](C(=O)O)N)O 分子...
NMDA receptor Medical Wikipedia Related to NMDA receptor:AMPA receptor,NMDA receptor antagonist (ĕn′ĕm′dē′ā′) n. A brain receptor activated by glutamate, which when excessively stimulated may cause cognitive defects in Alzheimer's disease. ...
liptons.a.,failuresandsuccessesofnmdareceptorantagonists:molecularbasisfortheuseofopen-channelblockerslikememantineinthetreatmentofacuteandchronicneurologicinsults.(nmda受体拮抗剂的失败和成功:使用美金刚等开放通道阻断剂在治疗急性和慢性神经损伤中的分子基础)neurorx.,1,101-110(2004). liptons.a.,paradigmshiftinne...
This study investigated the excitotoxic properties of a novel series of NMDA analogues in which a methyl group was introduced to the 5-position of the pyrrolidine ring of L-trans-2,3-PDC, a previously identified NMDA receptor agonist. While all of these compounds induced NMDA-receptor-mediated...
英文名:D-Serine;endogenous NMDA receptor co-agonist;β-Hydroxyalanine;(R)-Serine;S-serine;NSC 77689;NSC-77689;NSC77689 CAS号:312-84-5 结构式:C([C@H](C(=O)O)N)O 分子式:C3H7NO3 分子量:105.09 闪点:192.6±25.1 °C 熔点:220°C ...
Methadone is a mu (μ) opioid receptor agonist used clinically in adults and children to manage opioid use disorder, neonatal abstinence syndrome, and acute and chronic pain. It is typically marketed as a racemic mixture of R‐ and S‐enantiomers. R‐methadone has 30‐to 50‐fold higher anal...
testandforcedswimmingtest,andimmunohistochemistry,andtheexpressionofNOSinhippocampusweretested.Theresultsshowedthatdepression—likebehaviorandtheexpressionofNOSincreasedinhippocampusinducedbyratsreceivingCUMSfor21daysorintra—hippocampalinjectionsofNMDAreceptoragonist.Intra—hippocampalinjectionofnoncompetitiveNMDAreceptor...
(105 mg). The dextromethorphan component of AUVELITY is an antagonist of the NMDA receptor (an ionotropic glutamate receptor) and a sigma-1 receptor agonist. These actions are thought to modulate glutamatergic neurotransmission. The bupropion component of AUVELITY is an aminoketone and CYP2D6 ...