参考文献: 1.Steuernagel B, Periyannan S K, Hernández-Pinzón I, et al. Rapid cloning of disease-resistance genes in plants using mutagenesis and sequence capture[J]. Nature biotechnology, 2016, 34(6): 652-655. 2.Periyannan...
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Nucleotide binding site, Leucine‐rich repeat Receptors (NLRs), are canonical resistance (R) genes in plants, fungi and animals, functioning as central (helper) and peripheral (sensor) genes in a signalling network. We investigate NLR evolution during the colonisation of novel habitats in a model...
In plants and animals, the NLR family of receptors perceives non-self and modified-self molecules inside host cells and mediates innate immune responses to microbial pathogens. Despite their similar biological functions and protein architecture, animal N
Plants have developed a two-tiered immune system to detect and respond to potential threats in their environment6,7. The first line of defence, known as pattern-triggered immunity, is initiated when membrane-resident pattern recognition receptors recognize evolutionary conserved microbe-derived molecular...
近日,权威学术期刊Nature Communications发表了澳大利亚悉尼大学Evans S。 Lagudah和Peng Zhang团队的最新相关研究成果,题为A recombined Sr26 and Sr61 disease resistance gene stack in wheat encodes unrelated NLR genes的研究论文。 欧洲和非洲小麦上的茎锈病的重新出现,加强了对持久抗性基因部署的持续需求。本研究从...
In the indirect model, NLR protein interacts with Transcriptional networks involved in effector triggered immunity A most rapid and early event in ETI is up- or downregulation of defense-responsive genes. The massive transcriptional reprogramming underpinning hypersensitive responses (HR) in Arabidopsis ...
All three properties likely apply to NLR proteins, although studies in plants and mammals might reveal distinct features. Plants have hundreds of NLR genes, and most are highly polymorphic in the LRR domain, so as to recognize the huge diversity of pathogen effectors. Acknowledgements We ...
A study of the evolution of disease resistance genes in agriculturally important plants such as Brassicas helps gain insights into their function and inform the identification of resistance genes for breeding of resistant lines.doi:10.1002/tpg2.20060Yueqi Zhang...
Plant intracellular NLR immune receptors can function individually or in pairs to detect pathogen effectors and activate immune responses. NLR homeostasis has to be tightly regulated to ensure proper defense without triggering autoimmunity. However, in c