Pan markersγδ TcellNKT CD3分泌因子 Granzyme B IFNγ IL-4● IL-5● IL-17A● Perforin TNFα● 分泌因子 IL-4↑● IL-10↑● IL-13↑● IL-17↑● IL-22↑● IL-21↑● IFNγ↑● TNFα↑● 细胞表面 CD25↑● CD27● CD28● CD44● CD45R(B220)↑● CD45RB● CD62L● CD69↑● CD...
NKT细胞(Natural killer T cell) 是指能够同时组成性表达CD56(小鼠NK1.1)和TCR-CD3复合受体的T细胞,在胸腺内或胸腺外(胚肝)分化发育。NKT细胞表面TCR表达密度较低,且缺乏多样性,抗原识别谱窄,可识别CD1分子所提呈的磷脂和糖脂类抗原,且不受MHC限制。NKT细胞是一类天然存在的介导先天性和获得性免疫应答的重要淋巴细...
Pan markersγδ TcellNKT CD3分泌因子 Granzyme B IFNγ IL-4● IL-5● IL-17A● Perforin TNFα● 分泌因子 IL-4↑● IL-10↑● IL-13↑● IL-17↑● IL-22↑● IL-21↑● IFNγ↑● TNFα↑● 细胞表面 CD25↑● CD27● CD28● CD44● CD45R(B220)↑● CD45RB● CD62L● CD69↑● CD...
Pan markersγδ TcellNKT CD3分泌因子 Granzyme B IFNγ IL-4● IL-5● IL-17A● Perforin TNFα● 分泌因子 IL-4↑● IL-10↑● IL-13↑● IL-17↑● IL-22↑● IL-21↑● IFNγ↑● TNFα↑● 细胞表面 CD25↑● CD27● CD28● CD44● CD45R(B220)↑● CD45RB● CD62L● CD69↑● CD...
CD3+ graft cell count influence on chronic GVHD in haploidentical allogeneic transplantation using post-transplant cyclophosphamide. Bone Marrow Transplant. 2018;53:1522–31. CAS PubMed Google Scholar Pirogova OV, Moiseev IS, Surkova EA, Lapin SV, Bondarenko SN, Kulagin AD, et al. Profiles of...
NKT细胞(Natural killer T cell) 是指能够同时组成性表达CD56(小鼠NK1.1)和TCR-CD3复合受体的T细胞,在胸腺内或胸腺外(胚肝)分化发育。NKT细胞表面TCR表达密度较低,且缺乏多样性,抗原识别谱窄,可识别CD1分子所提呈的磷脂和糖脂类抗原,且不受MHC限制。NKT细胞是一类天然存在的介导先天性和获得性免疫应答的重要淋巴细...
αβ-T cell receptor+ CD4−CD8− T cells produce IL-4. J. Immunol. 149, 1211–1215 (1992). CAS PubMed Google Scholar Sykes, M. Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4−CD8− and αβ TCR+NK1.1+ cells. J. Immunol. 145, 3209–3215 (...
We also highlight the hazards of using surrogate phenotypes, none of which accurately identify NKT cens, and one in particular (DX5~+CD3~+) actuany excludes these cens. Finany, our results support the concept that NK1.1 expression may not be an ideal marker for CD1d-restricted NKT cens, ...
关键词:URSANKT细胞z汹弋叫、鼠冁型 圭墨蔓三曼型查堂堡主丝塞DysfunctionofNKTcellsinmurinemodelofunexplainedrecurrentspontaneousabortionAbstractAsubpopulationofTlymphocytesisnamednaturalkillerTcell(shorterfornaturalkillerTcell),becauseitsharesNKcellmarker.ThephenotypeofNKTcellsisCD3+a13TCR+,andeitherCD4+orCD4。
et al. Defective development of NK1.1+ T-cell antigen receptor αβ+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+ CD3– NK-like cells in the thymus. Blood 97, 1765–1775 (2001). CAS PubMed Google Scholar Seiler, M. P. et al. Elevated and sustained...